Emergence of a KPC-90 Variant that Confers Resistance to Ceftazidime-Avibactam in an ST463 Carbapenem-Resistant Pseudomonas aeruginosa Strain

Emergence of a KPC-90 Variant that Confers Resistance to Ceftazidime-Avibactam in an ST463 Carbapenem-Resistant Pseudomonas aeruginosa Strain

ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has become a serious challenge in the clinic. Recently, the prevalence of CRPA isolates carrying the blaKPC-2 gene has been increasing in China. Ceftazidime-avibactam (CZA) has shown good efficacy against large portions of KPC-2-producing C...

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Bibliographic Details
Main Authors: Yuexing Tu, Dairong Wang, Yiwei Zhu, Jiayan Li, Yan Jiang, Wenhao Wu, Xi Li, Hua Zhou
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
ceftazidime-avibactam
resistance
CRPA
KPC-90
ST463
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01869-21

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