Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing

Pharmacokinetics of baicalin and oroxyloside in plasma and different tissues of rats after transnasal aerosol inhalation and intravenous injection of Tanreqing

To avoid adverse drug reactions associated with injection, off-label nebulization of Tanreqing (TRQ) injection is often used in China to treat respiratory diseases. However, the aerodynamic properties and lung availability of TRQ aerosols remain largely uninvestigated. This study aimed to investigat...

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Bibliographic Details
Main Authors: Teng-Fei Chen, Ling Song, Yun-Hang Gao, Han Li, Jian-Liang Li, Hong-Ping Hou, Bo Peng, Hui-Ying Wang, Wen-Hao Cheng, Zu-Guang Ye, Ying-Fei Li, Guang-Ping Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
baicalin
lung
oroxyloside
pharmacokinetics
Tanreqing
transnasal aerosol inhalation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.951613/full

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