Effective connectivity underlying neural and behavioral components of prism adaptation
Prism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lack...
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.915260/full |
| _version_ | 1811301284860395520 |
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| author | Selene Schintu Selene Schintu Selene Schintu Stephen J. Gotts Michael Freedberg Sarah Shomstein Eric M. Wassermann |
| author_facet | Selene Schintu Selene Schintu Selene Schintu Stephen J. Gotts Michael Freedberg Sarah Shomstein Eric M. Wassermann |
| author_sort | Selene Schintu |
| collection | DOAJ |
| description | Prism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lacking. We employed Structural Equation Modeling (SEM), a form of effective connectivity analysis, to establish directionality among connected nodes of the brain network thought to subserve PA. The findings reveal two distinct network branches: (1) a loop involving connections from the parietal cortices to the right parahippocampal gyrus, and (2) a branch linking the lateral premotor cortex to the parahippocampal gyrus via the cerebellum. Like the sensorimotor aftereffects, the first branch exhibited qualitatively different modulations for left versus right PA, and critically, changes in these connections were correlated with the magnitude of the sensorimotor aftereffects. Like the cognitive aftereffects, changes in the second branch were qualitatively similar for left and right PA, with greater change for left PA and a trend correlation with cognitive aftereffects. These results provide direct evidence that PA is supported by two functionally distinct subnetworks, a parietal–temporal network responsible for sensorimotor aftereffects and a fronto-cerebellar network responsible for cognitive aftereffects. |
| first_indexed | 2024-04-13T07:06:01Z |
| format | Article |
| id | doaj.art-df8d60a8b7c24df9a75a405e954e7c9f |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-04-13T07:06:01Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-df8d60a8b7c24df9a75a405e954e7c9f2022-12-22T02:56:59ZengFrontiers Media S.A.Frontiers in Psychology1664-10782022-09-011310.3389/fpsyg.2022.915260915260Effective connectivity underlying neural and behavioral components of prism adaptationSelene Schintu0Selene Schintu1Selene Schintu2Stephen J. Gotts3Michael Freedberg4Sarah Shomstein5Eric M. Wassermann6Behavioral Neurology Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD, United StatesDepartment of Psychological and Brain Sciences, The George Washington University, Washington, DC, United StatesCenter for Mind/Brain Sciences-CIMeC, University of Trento, Rovereto, Trentino, ItalyLaboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, United StatesDepartment of Kinesiology and Health Education, University of Texas at Austin, Austin, TX, United StatesDepartment of Psychological and Brain Sciences, The George Washington University, Washington, DC, United StatesBehavioral Neurology Unit, National Institute of Neurological Disorders and Stroke, Bethesda, MD, United StatesPrism adaptation (PA) is a form of visuomotor training that produces both sensorimotor and cognitive aftereffects depending on the direction of the visual displacement. Recently, a neural framework explaining both types of PA-induced aftereffects has been proposed, but direct evidence for it is lacking. We employed Structural Equation Modeling (SEM), a form of effective connectivity analysis, to establish directionality among connected nodes of the brain network thought to subserve PA. The findings reveal two distinct network branches: (1) a loop involving connections from the parietal cortices to the right parahippocampal gyrus, and (2) a branch linking the lateral premotor cortex to the parahippocampal gyrus via the cerebellum. Like the sensorimotor aftereffects, the first branch exhibited qualitatively different modulations for left versus right PA, and critically, changes in these connections were correlated with the magnitude of the sensorimotor aftereffects. Like the cognitive aftereffects, changes in the second branch were qualitatively similar for left and right PA, with greater change for left PA and a trend correlation with cognitive aftereffects. These results provide direct evidence that PA is supported by two functionally distinct subnetworks, a parietal–temporal network responsible for sensorimotor aftereffects and a fronto-cerebellar network responsible for cognitive aftereffects.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.915260/fullvisuospatial attentionvisuomotor adaptationparahippocampal gyrussensorimotor adaptationposterior parietal cortexnavigation network |
| spellingShingle | Selene Schintu Selene Schintu Selene Schintu Stephen J. Gotts Michael Freedberg Sarah Shomstein Eric M. Wassermann Effective connectivity underlying neural and behavioral components of prism adaptation Frontiers in Psychology visuospatial attention visuomotor adaptation parahippocampal gyrus sensorimotor adaptation posterior parietal cortex navigation network |
| title | Effective connectivity underlying neural and behavioral components of prism adaptation |
| title_full | Effective connectivity underlying neural and behavioral components of prism adaptation |
| title_fullStr | Effective connectivity underlying neural and behavioral components of prism adaptation |
| title_full_unstemmed | Effective connectivity underlying neural and behavioral components of prism adaptation |
| title_short | Effective connectivity underlying neural and behavioral components of prism adaptation |
| title_sort | effective connectivity underlying neural and behavioral components of prism adaptation |
| topic | visuospatial attention visuomotor adaptation parahippocampal gyrus sensorimotor adaptation posterior parietal cortex navigation network |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.915260/full |
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