Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction?
To examine the value of surveillance urethro-cystoscopy in patients with neurogenic lower urinary tract dysfunction (NLUTD) in regard to the conflicting literature as it is generally agreed that patients with NLUTD are at increased risk for bladder cancer.In a cross-sectional study, a consecutive se...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4626398?pdf=render |
| _version_ | 1811306097352376320 |
|---|---|
| author | Ulla Sammer Matthias Walter Stephanie C Knüpfer Ulrich Mehnert Beata Bode-Lesniewska Thomas M Kessler |
| author_facet | Ulla Sammer Matthias Walter Stephanie C Knüpfer Ulrich Mehnert Beata Bode-Lesniewska Thomas M Kessler |
| author_sort | Ulla Sammer |
| collection | DOAJ |
| description | To examine the value of surveillance urethro-cystoscopy in patients with neurogenic lower urinary tract dysfunction (NLUTD) in regard to the conflicting literature as it is generally agreed that patients with NLUTD are at increased risk for bladder cancer.In a cross-sectional study, a consecutive series of 129 patients (50 females, 79 males, mean age 51, range 18-88) suffering from NLUTD for at least 5 years was prospectively investigated using urethro-cystoscopy and bladder washing cytology at a single university spinal cord injury (SCI) center.Due to suspicious urethro-cystoscopy and/or bladder washing cytology findings, 13 (10%) of 129 patients underwent transurethral resection of the bladder lesion and/or random bladder biopsies. Overall, 9 relevant histological findings were found in 5% (7/129) of our patients: bladder melanosis (n = 1), nephrogenic adenoma (n = 3), keratinizing squamous metaplasia (n = 1), intestinal metaplasia (n = 3), and muscle-invasive adenocarcinoma of the bladder (n = 1).Using surveillance urethro-cystoscopy, we found relevant histological findings in 5% of our patients suffering from NLUTD for at least 5 years. Thus, surveillance urethro-cystoscopy might be warranted, although the ideal starting point and frequency remain to be determined in further prospective studies. |
| first_indexed | 2024-04-13T08:38:19Z |
| format | Article |
| id | doaj.art-df902bf4bcfc47b396fe8726df5d7572 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T08:38:19Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-df902bf4bcfc47b396fe8726df5d75722022-12-22T02:54:00ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-011010e014097010.1371/journal.pone.0140970Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction?Ulla SammerMatthias WalterStephanie C KnüpferUlrich MehnertBeata Bode-LesniewskaThomas M KesslerTo examine the value of surveillance urethro-cystoscopy in patients with neurogenic lower urinary tract dysfunction (NLUTD) in regard to the conflicting literature as it is generally agreed that patients with NLUTD are at increased risk for bladder cancer.In a cross-sectional study, a consecutive series of 129 patients (50 females, 79 males, mean age 51, range 18-88) suffering from NLUTD for at least 5 years was prospectively investigated using urethro-cystoscopy and bladder washing cytology at a single university spinal cord injury (SCI) center.Due to suspicious urethro-cystoscopy and/or bladder washing cytology findings, 13 (10%) of 129 patients underwent transurethral resection of the bladder lesion and/or random bladder biopsies. Overall, 9 relevant histological findings were found in 5% (7/129) of our patients: bladder melanosis (n = 1), nephrogenic adenoma (n = 3), keratinizing squamous metaplasia (n = 1), intestinal metaplasia (n = 3), and muscle-invasive adenocarcinoma of the bladder (n = 1).Using surveillance urethro-cystoscopy, we found relevant histological findings in 5% of our patients suffering from NLUTD for at least 5 years. Thus, surveillance urethro-cystoscopy might be warranted, although the ideal starting point and frequency remain to be determined in further prospective studies.http://europepmc.org/articles/PMC4626398?pdf=render |
| spellingShingle | Ulla Sammer Matthias Walter Stephanie C Knüpfer Ulrich Mehnert Beata Bode-Lesniewska Thomas M Kessler Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? PLoS ONE |
| title | Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? |
| title_full | Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? |
| title_fullStr | Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? |
| title_full_unstemmed | Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? |
| title_short | Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? |
| title_sort | do we need surveillance urethro cystoscopy in patients with neurogenic lower urinary tract dysfunction |
| url | http://europepmc.org/articles/PMC4626398?pdf=render |
| work_keys_str_mv | AT ullasammer doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction AT matthiaswalter doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction AT stephaniecknupfer doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction AT ulrichmehnert doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction AT beatabodelesniewska doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction AT thomasmkessler doweneedsurveillanceurethrocystoscopyinpatientswithneurogeniclowerurinarytractdysfunction |