Nephroblastoma in Older Adult: Case Report and Review of Literature
Introduction: Nephroblastoma, or Wilms’ tumor, is a malignant renal neoplasm commonly found in children, is extremely rare in adults representing only 0.5% of all renal neoplasms. Adult Wilms tumor is rare, to our knowledge fewer than 300 cases have been reported in the English literature to date. H...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2024-07-01
|
| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | https://beta.karger.com/Article/FullText/540279 |
| _version_ | 1827132120108105728 |
|---|---|
| author | Ricardo Fernández-Ferreira Jose Manuel Torres-Zazueta César Martínez-Medrano Adrián Meléndez-Mendoza Sonia Tavares-García María Alejandra Muñoz Rubiano Gredel Portela-Rubio Julieta Robles-Castro Jorge Alberto Robles-Aviña Jose Manuel Ruiz Morales |
| author_facet | Ricardo Fernández-Ferreira Jose Manuel Torres-Zazueta César Martínez-Medrano Adrián Meléndez-Mendoza Sonia Tavares-García María Alejandra Muñoz Rubiano Gredel Portela-Rubio Julieta Robles-Castro Jorge Alberto Robles-Aviña Jose Manuel Ruiz Morales |
| author_sort | Ricardo Fernández-Ferreira |
| collection | DOAJ |
| description | Introduction: Nephroblastoma, or Wilms’ tumor, is a malignant renal neoplasm commonly found in children, is extremely rare in adults representing only 0.5% of all renal neoplasms. Adult Wilms tumor is rare, to our knowledge fewer than 300 cases have been reported in the English literature to date. However, in older adults after 60 years of age, only less than 45 cases have been reported. For this reason, treatment guidelines in adults still are lacking. Prognosis in nephroblastoma for adult patients is found to be worse than in children. Case Presentation: We report the case of a 65-year-old female with lumbar fossa mass, flank pain and hematuria, and pathologic diagnosis of Wilms tumor. We performed nephrectomy. No adjuvant treatment was given. Our patient remains asymptomatic and without evidence of recurrence 12 months after the surgery. Conclusion: Nephroblastoma in the elderly presents different clinical behavior and prognosis compared to nephroblastoma in children. |
| first_indexed | 2025-03-20T16:42:55Z |
| format | Article |
| id | doaj.art-df919b0a49f648d789bc39725ee2702f |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2025-03-20T16:42:55Z |
| publishDate | 2024-07-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-df919b0a49f648d789bc39725ee2702f2024-08-29T09:04:14ZengKarger PublishersCase Reports in Oncology1662-65752024-07-0117181883010.1159/000540279540279Nephroblastoma in Older Adult: Case Report and Review of LiteratureRicardo Fernández-Ferreira0Jose Manuel Torres-Zazueta1César Martínez-Medrano2Adrián Meléndez-Mendoza3Sonia Tavares-García4María Alejandra Muñoz Rubiano5Gredel Portela-Rubio6Julieta Robles-Castro7Jorge Alberto Robles-Aviña8Jose Manuel Ruiz Morales9https://orcid.org/0000-0003-3512-7776Oncology Medicine and Surgical Oncology Department. Central South High Specialty Hospital PEMEX, Mexico City, MexicoUrology Service, Centro Médico Nacional Siglo XXI, IMSS, Instituto Mexicano del Seguro Social, Mexico City, MexicoFaculty of Medicine, National Autonomous University of Mexico, Mexico City, MexicoFaculty of Medicine, National Autonomous University of Mexico, Mexico City, MexicoPatology Department. Centro Médico Nacional Siglo XXI, IMSS, Instituto Mexicano del Seguro Social, Mexico City, MexicoUrology Service, Centro Médico Nacional Siglo XXI, IMSS, Instituto Mexicano del Seguro Social, Mexico City, MexicoOncology Medicine and Surgical Oncology Department. Central South High Specialty Hospital PEMEX, Mexico City, MexicoOncology Medicine and Surgical Oncology Department. Central South High Specialty Hospital PEMEX, Mexico City, MexicoOncology Medicine and Surgical Oncology Department. Central South High Specialty Hospital PEMEX, Mexico City, MexicoOncology Medicine Department, Medica Sur Hospital, Mexico City, MexicoIntroduction: Nephroblastoma, or Wilms’ tumor, is a malignant renal neoplasm commonly found in children, is extremely rare in adults representing only 0.5% of all renal neoplasms. Adult Wilms tumor is rare, to our knowledge fewer than 300 cases have been reported in the English literature to date. However, in older adults after 60 years of age, only less than 45 cases have been reported. For this reason, treatment guidelines in adults still are lacking. Prognosis in nephroblastoma for adult patients is found to be worse than in children. Case Presentation: We report the case of a 65-year-old female with lumbar fossa mass, flank pain and hematuria, and pathologic diagnosis of Wilms tumor. We performed nephrectomy. No adjuvant treatment was given. Our patient remains asymptomatic and without evidence of recurrence 12 months after the surgery. Conclusion: Nephroblastoma in the elderly presents different clinical behavior and prognosis compared to nephroblastoma in children.https://beta.karger.com/Article/FullText/540279nephroblastomawilms’ tumormetanephric blastemanephrectomyrenal neoplasms |
| spellingShingle | Ricardo Fernández-Ferreira Jose Manuel Torres-Zazueta César Martínez-Medrano Adrián Meléndez-Mendoza Sonia Tavares-García María Alejandra Muñoz Rubiano Gredel Portela-Rubio Julieta Robles-Castro Jorge Alberto Robles-Aviña Jose Manuel Ruiz Morales Nephroblastoma in Older Adult: Case Report and Review of Literature Case Reports in Oncology nephroblastoma wilms’ tumor metanephric blastema nephrectomy renal neoplasms |
| title | Nephroblastoma in Older Adult: Case Report and Review of Literature |
| title_full | Nephroblastoma in Older Adult: Case Report and Review of Literature |
| title_fullStr | Nephroblastoma in Older Adult: Case Report and Review of Literature |
| title_full_unstemmed | Nephroblastoma in Older Adult: Case Report and Review of Literature |
| title_short | Nephroblastoma in Older Adult: Case Report and Review of Literature |
| title_sort | nephroblastoma in older adult case report and review of literature |
| topic | nephroblastoma wilms’ tumor metanephric blastema nephrectomy renal neoplasms |
| url | https://beta.karger.com/Article/FullText/540279 |
| work_keys_str_mv | AT ricardofernandezferreira nephroblastomainolderadultcasereportandreviewofliterature AT josemanueltorreszazueta nephroblastomainolderadultcasereportandreviewofliterature AT cesarmartinezmedrano nephroblastomainolderadultcasereportandreviewofliterature AT adrianmelendezmendoza nephroblastomainolderadultcasereportandreviewofliterature AT soniatavaresgarcia nephroblastomainolderadultcasereportandreviewofliterature AT mariaalejandramunozrubiano nephroblastomainolderadultcasereportandreviewofliterature AT gredelportelarubio nephroblastomainolderadultcasereportandreviewofliterature AT julietaroblescastro nephroblastomainolderadultcasereportandreviewofliterature AT jorgealbertoroblesavina nephroblastomainolderadultcasereportandreviewofliterature AT josemanuelruizmorales nephroblastomainolderadultcasereportandreviewofliterature |