Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses
<p class="p1">Azacitidine (5-azacytidine, VIDAZA<span class="s1">®</span>) is a disease-modifying agent that improves survival, reduces transfusion dependence, and reduces progression to acute myeloid leukemia in patients with higher risk myelodysplastic syndrom...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pappin Communications
2012-11-01
|
| Series: | Canadian Oncology Nursing Journal |
| Online Access: | https://canadianoncologynursingjournal.com/index.php/conj/article/view/112 |
| _version_ | 1797320050942672896 |
|---|---|
| author | Cindy Murray Annie Wereley Shannon Nixon Carol Hua-Yung Sarah von Riedemann Sandra Kurtin |
| author_facet | Cindy Murray Annie Wereley Shannon Nixon Carol Hua-Yung Sarah von Riedemann Sandra Kurtin |
| author_sort | Cindy Murray |
| collection | DOAJ |
| description | <p class="p1">Azacitidine (5-azacytidine, VIDAZA<span class="s1">®</span>) is a disease-modifying agent that improves survival, reduces transfusion dependence, and reduces progression to acute myeloid leukemia in patients with higher risk myelodysplastic syndromes. Azacitidine injection is associated with characteristic adverse events (AEs) that must be managed in order for patients to stay on therapy and achieve optimal therapeutic outcomes. These AEs include injection-site reactions, cytopenias, and gastrointestinal effects. Oncology nurses are uniquely positioned to provide patient support and counselling, thereby helping patients and their families set clear expectations for azacitidine therapy. This article presents a nursing standard designed to support Canadian oncology nurses in the key areas of counselling for patients initiating and continuing azacitidine, as well as nursing strategies for prevention and management of azacitidine-associated AEs. Many of the general principles discussed in this nursing standard can be applied broadly to many diseases and treatments.</p> |
| first_indexed | 2024-03-08T04:16:00Z |
| format | Article |
| id | doaj.art-df92019697eb4a57adc13370af2cef5c |
| institution | Directory Open Access Journal |
| issn | 1181-912X 2368-8076 |
| language | English |
| last_indexed | 2024-03-08T04:16:00Z |
| publishDate | 2012-11-01 |
| publisher | Pappin Communications |
| record_format | Article |
| series | Canadian Oncology Nursing Journal |
| spelling | doaj.art-df92019697eb4a57adc13370af2cef5c2024-02-08T16:28:53ZengPappin CommunicationsCanadian Oncology Nursing Journal1181-912X2368-80762012-11-01224222227110Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nursesCindy MurrayAnnie WereleyShannon NixonCarol Hua-YungSarah von RiedemannSandra Kurtin<p class="p1">Azacitidine (5-azacytidine, VIDAZA<span class="s1">®</span>) is a disease-modifying agent that improves survival, reduces transfusion dependence, and reduces progression to acute myeloid leukemia in patients with higher risk myelodysplastic syndromes. Azacitidine injection is associated with characteristic adverse events (AEs) that must be managed in order for patients to stay on therapy and achieve optimal therapeutic outcomes. These AEs include injection-site reactions, cytopenias, and gastrointestinal effects. Oncology nurses are uniquely positioned to provide patient support and counselling, thereby helping patients and their families set clear expectations for azacitidine therapy. This article presents a nursing standard designed to support Canadian oncology nurses in the key areas of counselling for patients initiating and continuing azacitidine, as well as nursing strategies for prevention and management of azacitidine-associated AEs. Many of the general principles discussed in this nursing standard can be applied broadly to many diseases and treatments.</p>https://canadianoncologynursingjournal.com/index.php/conj/article/view/112 |
| spellingShingle | Cindy Murray Annie Wereley Shannon Nixon Carol Hua-Yung Sarah von Riedemann Sandra Kurtin Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses Canadian Oncology Nursing Journal |
| title | Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses |
| title_full | Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses |
| title_fullStr | Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses |
| title_full_unstemmed | Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses |
| title_short | Counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy: A practice standard for Canadian nurses |
| title_sort | counselling and adverse event management for patients with myelodysplastic syndromes undergoing azacitidine therapy a practice standard for canadian nurses |
| url | https://canadianoncologynursingjournal.com/index.php/conj/article/view/112 |
| work_keys_str_mv | AT cindymurray counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses AT anniewereley counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses AT shannonnixon counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses AT carolhuayung counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses AT sarahvonriedemann counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses AT sandrakurtin counsellingandadverseeventmanagementforpatientswithmyelodysplasticsyndromesundergoingazacitidinetherapyapracticestandardforcanadiannurses |