Preservation of microvascular barrier function requires CD31 receptor-induced metabolic reprogramming
The mechanisms that restore endothelial barrier integrity following inflammation-induced breaching are incompletely understood. Here the authors show that the CD31 immune receptor contributes to reestablishing vascular integrity via its effects on endothelial cell metabolism.
Bibliographic Details
| Main Authors: |
Kenneth C. P. Cheung,
Silvia Fanti,
Claudio Mauro,
Guosu Wang,
Anitha S. Nair,
Hongmei Fu,
Silvia Angeletti,
Silvia Spoto,
Marta Fogolari,
Francesco Romano,
Dunja Aksentijevic,
Weiwei Liu,
Baiying Li,
Lixin Cheng,
Liwen Jiang,
Juho Vuononvirta,
Thanushiyan R. Poobalasingam,
David M. Smith,
Massimo Ciccozzi,
Egle Solito,
Federica M. Marelli-Berg |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17329-8
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