Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy

Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy

Abstract Background Metastatic melanoma has a high mortality rate and poor survival. This is associated with efficient metastatic colonization, but the underlying mechanisms remain elusive. Communication between cancer stem cells (CSCs) and cancer cells plays an important role in metastatic dissemin...

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Bibliographic Details
Main Authors: Xiaoshuang Li, Doudou Liu, Hao Chen, Bin Zeng, Qiting Zhao, Yuhan Zhang, Yuting Chen, Jianyu Wang, H. Rosie Xing
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Biological Research
Subjects:
Melanoma stem cells
Exosomes
miR-1268a
Metastasis
Autophagy
Online Access:https://doi.org/10.1186/s40659-022-00397-z

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