Antimicrobial Properties and Cytotoxic Effect of Imidazolium Geminis with Tunable Hydrophobicity

Antimicrobial Properties and Cytotoxic Effect of Imidazolium Geminis with Tunable Hydrophobicity

Antimicrobial, membranotropic and cytotoxic properties of dicationic imidazolium surfactants of n-s-n (Im) series with variable length of alkyl group (n = 8, 10, 12, 14, 16) and spacer fragment (s = 2, 3, 4) were explored and compared with monocationic analogues. Their activity against a representat...

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Bibliographic Details
Main Authors: Syumbelya K. Amerkhanova, Alexandra D. Voloshina, Alla B. Mirgorodskaya, Anna P. Lyubina, Darya A. Kuznetsova, Rushana A. Kushnazarova, Vasilii A. Mikhailov, Lucia Ya. Zakharova
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
dicationic imidazolium surfactants
antimicrobial activity
cytotoxicity
hemolysis
antimicrobial resistance
selectivity
Online Access:https://www.mdpi.com/1422-0067/22/23/13148

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