Insight into the regulation of NLRP3 inflammasome activation by mitochondria in liver injury and the protective role of natural products

Due to high mortality rates and poor prognosis, liver injury remains one of the leading causes of mortality worldwide. Amounting evidence suggested that the activation of the nucleotide-binding oligomerization domain (NOD)-like receptor containing pyrin domain 3 (NLRP3) inflammasome, which promotes...

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Bibliographic Details
Main Authors: Yu Liu, Zi-wei Guo, Jian Li, Ai-hong Li, Tao-guang Huo
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222013579