The aryl hydrocarbon receptor controls mesenchymal stromal cell-mediated immunomodulation via ubiquitination of eukaryotic elongation factor-2 kinase

The aryl hydrocarbon receptor controls mesenchymal stromal cell-mediated immunomodulation via ubiquitination of eukaryotic elongation factor-2 kinase

Abstract Mesenchymal stem cells (MSCs) have great therapeutic advantages due to their immunosuppressive properties. The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor whose signaling plays an important role in the immune system. AHR may be involved in the regulation of MS...

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Main Authors: Enkhmaa Lkhagva-Yondon, Myeong Seong Seo, Yena Oh, Jonghun Jung, Eunhae Jeon, Kwangmin Na, Hyun Seung Yoo, Woo Chul Kim, Charlotte Esser, Sun U. Song, Myung-Shin Jeon
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06341-7

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