Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers
Seminal plasma is a potential source of biomarkers for many disorders of the male reproductive system including male infertility. Knowledge of the peptide and protein components of seminal fluid is accumulating especially with the appearance of highthroughput MS-based techniques. Of special interest...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2012-12-01
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| Series: | Balkan Journal of Medical Genetics |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/v10034-012-0016-9 |
| _version_ | 1797718708353761280 |
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| author | Davalieva Katarina Kiprijanovska S Noveski P Plaseska-Karanfilska D Plaseski T Kocevska B |
| author_facet | Davalieva Katarina Kiprijanovska S Noveski P Plaseska-Karanfilska D Plaseski T Kocevska B |
| author_sort | Davalieva Katarina |
| collection | DOAJ |
| description | Seminal plasma is a potential source of biomarkers for many disorders of the male reproductive system including male infertility. Knowledge of the peptide and protein components of seminal fluid is accumulating especially with the appearance of highthroughput MS-based techniques. Of special interest in the field of male infertility biomarkers, is the identification and characterization of differentially expressed proteins in seminal plasma of men with normal and impaired spermatogenesis. However, the data obtained until now is still quite heterogeneous and with small percentage of overlap between independent studies. Extensive comparative analysis of seminal plasma proteome is still needed in order to establish a potential link between seminal plasma proteins and male infertility. |
| first_indexed | 2024-03-12T08:54:18Z |
| format | Article |
| id | doaj.art-dfa941118a464c40a6f85499dd3dee88 |
| institution | Directory Open Access Journal |
| issn | 1311-0160 |
| language | English |
| last_indexed | 2024-03-12T08:54:18Z |
| publishDate | 2012-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Balkan Journal of Medical Genetics |
| spelling | doaj.art-dfa941118a464c40a6f85499dd3dee882023-09-02T16:10:16ZengSciendoBalkan Journal of Medical Genetics1311-01602012-12-0115Supplement353810.2478/v10034-012-0016-9Human Seminal Plasma Proteome Study: a Search for Male Infertility BiomarkersDavalieva Katarina0Kiprijanovska S1Noveski P2Plaseska-Karanfilska D3Plaseski T4Kocevska B5Research Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov,” Macedonian Academy of Sciences and Arts, 1000 Skopje, Republic of MacedoniaResearch Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov,” Macedonian Academy of Sciences and Arts, 1000 Skopje, Republic of MacedoniaResearch Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov,” Macedonian Academy of Sciences and Arts, 1000 Skopje, Republic of MacedoniaResearch Centre for Genetic Engineering and Biotechnology “Georgi D. Efremov,” Macedonian Academy of Sciences and Arts, 1000 Skopje, Republic of MacedoniaEndocrinology and Metabolic Disorders Clinic, Faculty of Medicine, Skopje, Republic of MacedoniaEndocrinology and Metabolic Disorders Clinic, Faculty of Medicine, Skopje, Republic of MacedoniaSeminal plasma is a potential source of biomarkers for many disorders of the male reproductive system including male infertility. Knowledge of the peptide and protein components of seminal fluid is accumulating especially with the appearance of highthroughput MS-based techniques. Of special interest in the field of male infertility biomarkers, is the identification and characterization of differentially expressed proteins in seminal plasma of men with normal and impaired spermatogenesis. However, the data obtained until now is still quite heterogeneous and with small percentage of overlap between independent studies. Extensive comparative analysis of seminal plasma proteome is still needed in order to establish a potential link between seminal plasma proteins and male infertility.https://doi.org/10.2478/v10034-012-0016-9biomarkersmale infertilitymass spectrometry (ms)matrix-assisted laser desorption/ ionization time of flight (maldi-tof)seminal plasmatwo-dimensional differential ingel electrophoresis (2-d dige)two- dimensional polyacrylamide gel electrophoresis (2-d page). |
| spellingShingle | Davalieva Katarina Kiprijanovska S Noveski P Plaseska-Karanfilska D Plaseski T Kocevska B Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers Balkan Journal of Medical Genetics biomarkers male infertility mass spectrometry (ms) matrix-assisted laser desorption/ ionization time of flight (maldi-tof) seminal plasma two-dimensional differential ingel electrophoresis (2-d dige) two- dimensional polyacrylamide gel electrophoresis (2-d page). |
| title | Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers |
| title_full | Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers |
| title_fullStr | Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers |
| title_full_unstemmed | Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers |
| title_short | Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers |
| title_sort | human seminal plasma proteome study a search for male infertility biomarkers |
| topic | biomarkers male infertility mass spectrometry (ms) matrix-assisted laser desorption/ ionization time of flight (maldi-tof) seminal plasma two-dimensional differential ingel electrophoresis (2-d dige) two- dimensional polyacrylamide gel electrophoresis (2-d page). |
| url | https://doi.org/10.2478/v10034-012-0016-9 |
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