Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

The present research is focused on developing floating matrix tablets of mitiglinide to prolong its gastric residence time for better absorption. Gastroretentive tablets were prepared using a direct compression technique with hydroxypropyl methylcellulose K15M (HPMC K15M) and sodium alginate as matr...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Meenakshi Patel, Santosh Shelke, Naazneen Surti, Prabhakar Panzade, Lamya Ahmed Al-Keridis, Tarun Kumar Upadhyay, Nawaf Alshammari, Mohd Saeed
Format:	Artikel
Sprache:	English
Veröffentlicht:	Frontiers Media S.A. 2023-03-01
Schriftenreihe:	Frontiers in Pharmacology
Schlagworte:	floating matrix tablet mitiglinide gastroretentive radiography factorial design
Online Zugang:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1140351/full

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