Design, preparation, and in vitro evaluation of gastroretentive floating matrix tablet of mitiglinide

The present research is focused on developing floating matrix tablets of mitiglinide to prolong its gastric residence time for better absorption. Gastroretentive tablets were prepared using a direct compression technique with hydroxypropyl methylcellulose K15M (HPMC K15M) and sodium alginate as matr...

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Bibliografiske detaljer
Main Authors: Meenakshi Patel, Santosh Shelke, Naazneen Surti, Prabhakar Panzade, Lamya Ahmed Al-Keridis, Tarun Kumar Upadhyay, Nawaf Alshammari, Mohd Saeed
Format: Article
Sprog:English
Udgivet: Frontiers Media S.A. 2023-03-01
Serier:Frontiers in Pharmacology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2023.1140351/full