Fucoidan from <i>Laminaria japonica</i> Ameliorates Type 2 Diabetes Mellitus in Association with Modulation of Gut Microbiota and Metabolites in Streptozocin-Treated Mice

Fucoidan from <i>Laminaria japonica</i> Ameliorates Type 2 Diabetes Mellitus in Association with Modulation of Gut Microbiota and Metabolites in Streptozocin-Treated Mice

Chronic diseases have been a leading cause of death worldwide, and polysaccharide supplementation is an effective therapeutic strategy for chronic diseases without adverse effects. In this study, the beneficial effect of <i>Laminaria japonica</i> fucoidan (LJF) on type 2 diabetes mellitu...

Full description

Bibliographic Details
Main Authors:	Chenxi Zhang, Jinhui Jia, Panpan Zhang, Weiyun Zheng, Xiaoming Guo, Chunqing Ai, Shuang Song
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	Foods
Subjects:	fucoidan <i>Laminaria japonica</i> gut microbiota and metabolites
Online Access:	https://www.mdpi.com/2304-8158/12/1/33

Similar Items

Inhibitory Effects of <i>Laminaria japonica</i> Fucoidans Against Noroviruses
by: Hyojin Kim, et al.
Published: (2020-09-01)

Preparation of Fucoidan from Laminaria japonica by Ethanol-free Extraction Process
by: Yanhong CHEN, et al.
Published: (2022-03-01)

<i>Laminaria japonica</i> Peptides Suppress Liver Cancer by Inducing Apoptosis: Possible Signaling Pathways and Mechanism
by: Yingzi Wu, et al.
Published: (2022-11-01)

Gut Microbiota of Individuals Could Be Balanced by a 14-Day Supplementation With Laminaria japonica and Differed in Metabolizing Alginate and Galactofucan
by: Xueqian Zhang, et al.
Published: (2022-05-01)

Renoprotective Effect of <i>Laminaria japonica</i> Polysaccharide in Adenine-Induced Chronic Renal Failure
by: Miao Long, et al.
Published: (2019-04-01)

Physicochemical Properties and Anticoagulant Activity of Purified Heteropolysaccharides from <i>Laminaria japonica</i>
by: Tingting Li, et al.
Published: (2022-05-01)

Toxicological Evaluation of Low Molecular Weight Fucoidan in Vitro and in Vivo
by: Pai-An Hwang, et al.
Published: (2016-06-01)

Physical Stress Induced Reduction of Proliferating Cells and Differentiated Neuroblasts Is Ameliorated by Fermented <i>Laminaria japonica</i> Extract Treatment
by: Hyo Young Jung, et al.
Published: (2020-11-01)

The Effect of <i>Laminaria japonica</i> on Metabolic Syndrome: A Systematic Review of Its Efficacy and Mechanism of Action
by: In-Seon Lee, et al.
Published: (2022-07-01)

Two <i>Laminaria japonica</i> Fermentation Broths Alleviate Oxidative Stress and Inflammatory Response Caused by UVB Damage: Photoprotective and Reparative Effects
by: Qianru Sun, et al.
Published: (2022-10-01)

Effects of Different Processing Methods on the Quality and Physicochemical Characteristics of <i>Laminaria japonica</i>
by: Zuomiao Yang, et al.
Published: (2023-04-01)

Cytotoxic Tricycloalternarene Compounds from Endophyte <i>Alternaria</i> sp. W-1 Associated with <i>Laminaria japonica</i>
by: Li Shen, et al.
Published: (2018-10-01)

Polysaccharides isolated from Laminaria japonica attenuates gestational diabetes mellitus by regulating the gut microbiota in mice
by: Huiting Lin, et al.
Published: (2021-06-01)

Inhibition of UVB-Induced Inflammation by <i>Laminaria japonica</i> Extract via Regulation of nc886-PKR Pathway
by: Kwang-Soo Lee, et al.
Published: (2020-06-01)

Carcinogenic and Non-Carcinogenic Health Risks Assessment of Elemental Contaminants in <I>Laminariae thalli</I>
by: V. M. Shchukin, et al.
Published: (2023-09-01)

The Potential Hypoglycemic Competence of Low Molecular Weight Polysaccharides Obtained from <i>Laminaria japonica</i>
by: Aijun Tong, et al.
Published: (2023-10-01)

Physicochemical Properties of the Soluble Dietary Fiber from <i>Laminaria japonica</i> and Its Role in the Regulation of Type 2 Diabetes Mice
by: Xixi Wang, et al.
Published: (2022-01-01)

Effect of Ultrasonic Irradiation on the Physicochemical and Structural Properties of <i>Laminaria japonica</i> Polysaccharides and Their Performance in Biological Activities
by: Jinhui Wu, et al.
Published: (2022-12-01)

Laminaria japonica extract inhibits VEGF-induced angiogenesis via binding with VEGF and regulation of VEGFR2 signaling pathway
by: Le-Le Yu, et al.
Published: (2024-02-01)

Correction: Zhang et al. Fucoidan from <i>Laminaria japonica</i> Ameliorates Type 2 Diabetes Mellitus in Association with Modulation of Gut Microbiota and Metabolites in Streptozocin-Treated Mice. <i>Foods</i> 2023, <i>12</i>, 33
by: Chenxi Zhang, et al.
Published: (2023-11-01)

Synthesis of porous carbon materials derived from laminaria japonica via simple carbonization and activation for supercapacitors
by: Youliang Cheng, et al.
Published: (2020-05-01)

<i>Laminaria japonica</i> Suppresses the Atopic Dermatitis-Like Responses in NC/Nga Mice and Inflamed HaCaT Keratinocytes via the Downregulation of STAT1
by: Youn-Hwan Hwang, et al.
Published: (2020-10-01)

Fucoidan Isolated from <i>Saccharina japonica</i> Inhibits LPS-Induced Inflammation in Macrophages via Blocking NF-κB, MAPK and JAK-STAT Pathways
by: Jing Ye, et al.
Published: (2020-06-01)

Cost-effective production of alginate oligosaccharides from Laminaria japonica roots by Pseudoalteromonas agarivorans A3
by: Xiao-Hui Sun, et al.
Published: (2023-09-01)

Effect of Microbial Fermentation on the Fishy-Odor Compounds in Kelp (<i>Laminaria japonica</i>)
by: Wenyang Zhu, et al.
Published: (2021-10-01)

Structural Characteristics and Immunomodulatory Effects of a Long-Chain Polysaccharide From Laminaria japonica
by: Jiamei Cui, et al.
Published: (2022-03-01)

Fermented Laminaria japonica improves working memory and antioxidant defense mechanism in healthy adults: a randomized, double-blind, and placebo-controlled clinical study
by: Young-Sang Kim, et al.
Published: (2022-08-01)

Bacillus subtilis-fermented brown seaweed Laminaria japonica inhibits foam cell formation via CD36-dependent signaling pathway
by: Hong-Ting Victor Lin, et al.
Published: (2024-04-01)

Chemical Composition and Antioxidant and Antibacterial Activities of an Essential Oil Extracted from an Edible Seaweed, Laminaria japonica L.
by: Jayanta Kumar Patra, et al.
Published: (2015-07-01)

Effects of the Brown Seaweed Laminaria japonica Supplementation on Serum Concentrations of IgG, Triglycerides, and Cholesterol, and Intestinal Microbiota Composition in Rats
by: Jae-Young Kim, et al.
Published: (2018-04-01)

Production Inhibition and Excretion Promotion of Urate by Fucoidan from <i>Laminaria japonica</i> in Adenine-Induced Hyperuricemic Mice
by: Dayan Zhang, et al.
Published: (2018-11-01)

Catalytic pyrolysis of <it>Laminaria japonica </it>over nanoporous catalysts using Py-GC/MS
by: Jeon Jong-Ki, et al.
Published: (2011-01-01)

Effects of Lactobacillus plantarum FZU3013-Fermented Laminaria japonica on Lipid Metabolism and Gut Microbiota in Hyperlipidaemic Rats
by: Jin-Peng Hu, et al.
Published: (2021-12-01)

ACE-inhibitory peptides from Laminaria japonica and their potential anti-hypertensive mechanism
by: Jie Wang, et al.
Published: (2021-01-01)

Ameliorative effect of dieckol-enriched extraction from Laminaria japonica on hepatic steatosis induced by a high-fat diet via β-oxidation pathway in ICR mice
by: Yixiang Liu, et al.
Published: (2019-07-01)

Biochemical Characterization of a New Oligoalginate Lyase and Its Biotechnological Application in Laminaria japonica Degradation
by: Shangyong Li, et al.
Published: (2020-03-01)

Antitumor Effect of Laminaria japonica Polysaccharide WLP5 in MCF-7 Breast Cancer Cell-Bearing Mice
by: CAO Mingyuan, LI Ying, QI Guohong, YANG Zhiping, HUANG Dechun, CHEN Guitang
Published: (2023-11-01)

Lactobacillus plantarum fermented Laminaria japonica alleviates UVB-induced epidermal photoinflammation via the Keap-1/Nrf2 pathway
by: Zixin Song, et al.
Published: (2023-08-01)

Antimicrobial activity of <i>Laminaria japonica</i> extracts against bacterial canker of tomato disease agent <i>Clavibacter michiganensis</i> subsp. <i>michiganensis</i>
by: Jin Cai, et al.
Published: (2017-05-01)

Effects of Fucoidan Isolated From Laminaria japonica on Immune Response and Gut Microbiota in Cyclophosphamide-Treated Mice
by: Yunping Tang, et al.
Published: (2022-05-01)