Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila

Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila

Alzheimer’s disease (AD) is the most common form of dementia and is characterized by intracellular neurofibrillary tangles of hyperphosphorylated Tau, including the 0N4R isoform and accumulation of extracellular amyloid beta (Aβ) plaques. However, less than 5% of AD cases are familial, with many add...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	James P. Higham, Bilal R. Malik, Edgar Buhl, Jennifer M. Dawson, Anna S. Ogier, Katie Lunnon, James J. L. Hodge
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2019-06-01
Sraith:	Frontiers in Cellular Neuroscience
Ábhair:	Alzheimer’s disease Drosophila memory lifespan locomotion neurodegeneration
Rochtain ar líne:	https://www.frontiersin.org/article/10.3389/fncel.2019.00260/full

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