Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia

Aggrephagy Deficiency in the Placenta: A New Pathogenesis of Preeclampsia

Aggrephagy is defined as the selective degradation of aggregated proteins by autophagosomes. Protein aggregation in organs and cells has been highlighted as a cause of multiple diseases, including neurodegenerative diseases, cardiac failure, and renal failure. Aggregates could pose a hazard for cell...

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Bibliographic Details
Main Authors: Akitoshi Nakashima, Tomoko Shima, Sayaka Tsuda, Aiko Aoki, Mihoko Kawaguchi, Atsushi Furuta, Ippei Yasuda, Satoshi Yoneda, Akemi Yamaki-Ushijima, Shi-Bin Cheng, Surendra Sharma, Shigeru Saito
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
aggrephagy
aggresome
autophagy
endoplasmic reticulum stress
inflammation
placenta
Online Access:https://www.mdpi.com/1422-0067/22/5/2432

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