Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination

Pulse oximetry is a non-invasive method for measuring blood oxygen saturation. However, its detection scheme heavily relies on single-point measurements. If the oxygen saturation is measured at a single location, the measurements are influenced by the profile of illumination, spatial variations in b...

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Main Authors: Riaz Muhammad, Kay Thwe Htun, Ezekiel Edward Nettey-Oppong, Ahmed Ali, Dae Keun Jeon, Hyun-Woo Jeong, Kyung Min Byun, Seung Ho Choi
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/23/7/3723
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author Riaz Muhammad
Kay Thwe Htun
Ezekiel Edward Nettey-Oppong
Ahmed Ali
Dae Keun Jeon
Hyun-Woo Jeong
Kyung Min Byun
Seung Ho Choi
author_facet Riaz Muhammad
Kay Thwe Htun
Ezekiel Edward Nettey-Oppong
Ahmed Ali
Dae Keun Jeon
Hyun-Woo Jeong
Kyung Min Byun
Seung Ho Choi
author_sort Riaz Muhammad
collection DOAJ
description Pulse oximetry is a non-invasive method for measuring blood oxygen saturation. However, its detection scheme heavily relies on single-point measurements. If the oxygen saturation is measured at a single location, the measurements are influenced by the profile of illumination, spatial variations in blood flow, and skin pigment. To overcome these issues, imaging systems that measure the distribution of oxygen saturation have been demonstrated. However, previous imaging systems have relied on red and near-infrared illuminations with different profiles, resulting in inconsistent ratios between transmitted red and near-infrared light over space. Such inconsistent ratios can introduce fundamental errors when calculating the spatial distribution of oxygen saturation. In this study, we developed a novel illumination system specifically designed for a pulse oximetry imaging system. For the illumination system, we customized the integrating sphere by coating a mixture of barium sulfate and white paint inside it and by coupling eight red and eight near-infrared LEDs. The illumination system created identical patterns of red and near-infrared illuminations that were spatially uniform. This allowed the ratio between transmitted red and near-infrared light to be consistent over space, enabling the calculation of the spatial distribution of oxygen saturation. We believe our developed pulse oximetry imaging system can be used to obtain spatial information on blood oxygen saturation that provides insight into the oxygenation of the blood contained within the peripheral region of the tissue.
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spelling doaj.art-dfb54b91c7c4430697956664b2a2e7f22023-11-17T17:36:49ZengMDPI AGSensors1424-82202023-04-01237372310.3390/s23073723Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength IlluminationRiaz Muhammad0Kay Thwe Htun1Ezekiel Edward Nettey-Oppong2Ahmed Ali3Dae Keun Jeon4Hyun-Woo Jeong5Kyung Min Byun6Seung Ho Choi7Department of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of KoreaDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of KoreaDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of KoreaDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of KoreaMediana, R&D Center, Wonju 26365, Republic of KoreaDepartment of Biomedical Engineering, Eulji University, Seongnam 13135, Republic of KoreaDepartment of Biomedical Engineering, Kyung Hee University, Yongin 17104, Republic of KoreaDepartment of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of KoreaPulse oximetry is a non-invasive method for measuring blood oxygen saturation. However, its detection scheme heavily relies on single-point measurements. If the oxygen saturation is measured at a single location, the measurements are influenced by the profile of illumination, spatial variations in blood flow, and skin pigment. To overcome these issues, imaging systems that measure the distribution of oxygen saturation have been demonstrated. However, previous imaging systems have relied on red and near-infrared illuminations with different profiles, resulting in inconsistent ratios between transmitted red and near-infrared light over space. Such inconsistent ratios can introduce fundamental errors when calculating the spatial distribution of oxygen saturation. In this study, we developed a novel illumination system specifically designed for a pulse oximetry imaging system. For the illumination system, we customized the integrating sphere by coating a mixture of barium sulfate and white paint inside it and by coupling eight red and eight near-infrared LEDs. The illumination system created identical patterns of red and near-infrared illuminations that were spatially uniform. This allowed the ratio between transmitted red and near-infrared light to be consistent over space, enabling the calculation of the spatial distribution of oxygen saturation. We believe our developed pulse oximetry imaging system can be used to obtain spatial information on blood oxygen saturation that provides insight into the oxygenation of the blood contained within the peripheral region of the tissue.https://www.mdpi.com/1424-8220/23/7/3723pulse oximetry imaging systemspatially uniform dual wavelength illuminationhyperspectral imaging system
spellingShingle Riaz Muhammad
Kay Thwe Htun
Ezekiel Edward Nettey-Oppong
Ahmed Ali
Dae Keun Jeon
Hyun-Woo Jeong
Kyung Min Byun
Seung Ho Choi
Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
Sensors
pulse oximetry imaging system
spatially uniform dual wavelength illumination
hyperspectral imaging system
title Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
title_full Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
title_fullStr Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
title_full_unstemmed Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
title_short Pulse Oximetry Imaging System Using Spatially Uniform Dual Wavelength Illumination
title_sort pulse oximetry imaging system using spatially uniform dual wavelength illumination
topic pulse oximetry imaging system
spatially uniform dual wavelength illumination
hyperspectral imaging system
url https://www.mdpi.com/1424-8220/23/7/3723
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