Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater
To monitor the presence of novel SARS-CoV-2 variants in New York City, Smyth et al. perform deep-sequencing of the receptor binding domain of S protein in wastewater samples and find novel cryptic lineages containing mutations affecting ACE2-tropism and showing decreased neutralization by antibodies...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28246-3 |
| _version_ | 1828424726794469376 |
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| author | Davida S. Smyth Monica Trujillo Devon A. Gregory Kristen Cheung Anna Gao Maddie Graham Yue Guan Caitlyn Guldenpfennig Irene Hoxie Sherin Kannoly Nanami Kubota Terri D. Lyddon Michelle Markman Clayton Rushford Kaung Myat San Geena Sompanya Fabrizio Spagnolo Reinier Suarez Emma Teixeiro Mark Daniels Marc C. Johnson John J. Dennehy |
| author_facet | Davida S. Smyth Monica Trujillo Devon A. Gregory Kristen Cheung Anna Gao Maddie Graham Yue Guan Caitlyn Guldenpfennig Irene Hoxie Sherin Kannoly Nanami Kubota Terri D. Lyddon Michelle Markman Clayton Rushford Kaung Myat San Geena Sompanya Fabrizio Spagnolo Reinier Suarez Emma Teixeiro Mark Daniels Marc C. Johnson John J. Dennehy |
| author_sort | Davida S. Smyth |
| collection | DOAJ |
| description | To monitor the presence of novel SARS-CoV-2 variants in New York City, Smyth et al. perform deep-sequencing of the receptor binding domain of S protein in wastewater samples and find novel cryptic lineages containing mutations affecting ACE2-tropism and showing decreased neutralization by antibodies. |
| first_indexed | 2024-12-10T16:22:05Z |
| format | Article |
| id | doaj.art-dfb729c6b3ac4f8d9b124404f8643c4a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-10T16:22:05Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-dfb729c6b3ac4f8d9b124404f8643c4a2022-12-22T01:41:47ZengNature PortfolioNature Communications2041-17232022-02-011311910.1038/s41467-022-28246-3Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewaterDavida S. Smyth0Monica Trujillo1Devon A. Gregory2Kristen Cheung3Anna Gao4Maddie Graham5Yue Guan6Caitlyn Guldenpfennig7Irene Hoxie8Sherin Kannoly9Nanami Kubota10Terri D. Lyddon11Michelle Markman12Clayton Rushford13Kaung Myat San14Geena Sompanya15Fabrizio Spagnolo16Reinier Suarez17Emma Teixeiro18Mark Daniels19Marc C. Johnson20John J. Dennehy21Department of Life Sciences, Texas A&M University-San AntonioDepartment of Biological Sciences and Geology, Queensborough Community College of The City University of New YorkDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineBiology Department, Queens College and The Graduate Center of The City University of New YorkBiology Department, Queens College and The Graduate Center of The City University of New YorkDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineBiology Department, Queens College and The Graduate Center of The City University of New YorkBiology Department, Queens College and The Graduate Center of The City University of New YorkBiology Department, Queens College and The Graduate Center of The City University of New YorkDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineBiology Department, Queens College and The Graduate Center of The City University of New YorkDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineBiology Department, Queens College and The Graduate Center of The City University of New YorkDepartment of Life Sciences, Texas A&M University-San AntonioDepartment of Biological & Environmental Sciences, Long Island University–Post, GreenvaleDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineDepartment of Molecular Microbiology and Immunology, University of Missouri-School of MedicineBiology Department, Queens College and The Graduate Center of The City University of New YorkTo monitor the presence of novel SARS-CoV-2 variants in New York City, Smyth et al. perform deep-sequencing of the receptor binding domain of S protein in wastewater samples and find novel cryptic lineages containing mutations affecting ACE2-tropism and showing decreased neutralization by antibodies.https://doi.org/10.1038/s41467-022-28246-3 |
| spellingShingle | Davida S. Smyth Monica Trujillo Devon A. Gregory Kristen Cheung Anna Gao Maddie Graham Yue Guan Caitlyn Guldenpfennig Irene Hoxie Sherin Kannoly Nanami Kubota Terri D. Lyddon Michelle Markman Clayton Rushford Kaung Myat San Geena Sompanya Fabrizio Spagnolo Reinier Suarez Emma Teixeiro Mark Daniels Marc C. Johnson John J. Dennehy Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater Nature Communications |
| title | Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater |
| title_full | Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater |
| title_fullStr | Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater |
| title_full_unstemmed | Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater |
| title_short | Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater |
| title_sort | tracking cryptic sars cov 2 lineages detected in nyc wastewater |
| url | https://doi.org/10.1038/s41467-022-28246-3 |
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