Periostin staining within renal tissues from IgA nephropathy patients
Periostin is a novel biomarker related to kidney disease progression. The aim of this study was to examine the level of periostin staining within renal tissue from IgA nephropathy patients. Immunohistochemistry for periostin was performed. The score of periostin staining and the correlation of per...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2018-02-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | https://rdo.psu.ac.th/sjstweb/journal/40-1/40-1-20.pdf |
| _version_ | 1818521498888962048 |
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| author | Peepattra Wantanasiri Bancha Satirapoj Mongkon Charoenpitakchai Pornanong Aramwit |
| author_facet | Peepattra Wantanasiri Bancha Satirapoj Mongkon Charoenpitakchai Pornanong Aramwit |
| author_sort | Peepattra Wantanasiri |
| collection | DOAJ |
| description | Periostin is a novel biomarker related to kidney disease progression. The aim of this study was to examine the
level of periostin staining within renal tissue from IgA nephropathy patients. Immunohistochemistry for periostin was
performed. The score of periostin staining and the correlation of periostin staining score with each pathological feature were
evaluated. Positive periostin staining was found in renal tissue from IgA nephropathy patients including glomerular,
interstitial, vascular and tubular areas. Tubular epithelial cell staining, tubular cell cast staining and periglomerular staining
were common histologic features positive for periostin. Periglomerular staining were correlated with interstitial fibrosis as
well as with tubular epithelial cell staining. In addition, tubular cell cast staining were correlated with tubular epithelial cell
staining as well as with tubular atrophy staining. We concluded that periostin may be a promising biomarker in IgA
nephropathy patients. |
| first_indexed | 2024-12-11T01:51:52Z |
| format | Article |
| id | doaj.art-dfba41b51f5f474bb9b1670c3410cdb5 |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-12-11T01:51:52Z |
| publishDate | 2018-02-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-dfba41b51f5f474bb9b1670c3410cdb52022-12-22T01:24:44ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952018-02-0140115516110.14456/sjst-psu.2018.20Periostin staining within renal tissues from IgA nephropathy patientsPeepattra Wantanasiri0Bancha Satirapoj1Mongkon Charoenpitakchai2Pornanong Aramwit3Bioactive Resources for Innovative Clinical Applications Research Unit, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathum Wan, Bangkok, 10330 ThailandDivision of Nephrology, Department of Medicine, Phramongkutklao Hospital, College of Medicine, Ratchathewi, Bangkok, 10400 ThailandDepartment of Pathology, Phramongkutklao Hospital, College of Medicine, Ratchathewi, Bangkok, 10400 ThailandBioactive Resources for Innovative Clinical Applications Research Unit, Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Pathum Wan, Bangkok, 10330 ThailandPeriostin is a novel biomarker related to kidney disease progression. The aim of this study was to examine the level of periostin staining within renal tissue from IgA nephropathy patients. Immunohistochemistry for periostin was performed. The score of periostin staining and the correlation of periostin staining score with each pathological feature were evaluated. Positive periostin staining was found in renal tissue from IgA nephropathy patients including glomerular, interstitial, vascular and tubular areas. Tubular epithelial cell staining, tubular cell cast staining and periglomerular staining were common histologic features positive for periostin. Periglomerular staining were correlated with interstitial fibrosis as well as with tubular epithelial cell staining. In addition, tubular cell cast staining were correlated with tubular epithelial cell staining as well as with tubular atrophy staining. We concluded that periostin may be a promising biomarker in IgA nephropathy patients.https://rdo.psu.ac.th/sjstweb/journal/40-1/40-1-20.pdfPeriostin stainingIgA nephropathyperiglomerular stainingtubular cell cast stainingtubular epithelial cell staining |
| spellingShingle | Peepattra Wantanasiri Bancha Satirapoj Mongkon Charoenpitakchai Pornanong Aramwit Periostin staining within renal tissues from IgA nephropathy patients Songklanakarin Journal of Science and Technology (SJST) Periostin staining IgA nephropathy periglomerular staining tubular cell cast staining tubular epithelial cell staining |
| title | Periostin staining within renal tissues from IgA nephropathy patients |
| title_full | Periostin staining within renal tissues from IgA nephropathy patients |
| title_fullStr | Periostin staining within renal tissues from IgA nephropathy patients |
| title_full_unstemmed | Periostin staining within renal tissues from IgA nephropathy patients |
| title_short | Periostin staining within renal tissues from IgA nephropathy patients |
| title_sort | periostin staining within renal tissues from iga nephropathy patients |
| topic | Periostin staining IgA nephropathy periglomerular staining tubular cell cast staining tubular epithelial cell staining |
| url | https://rdo.psu.ac.th/sjstweb/journal/40-1/40-1-20.pdf |
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