Automatic determination of lung features of CF patients in CT scans

This paper describes a prototype of an automatic system for the detection and evaluation of Cystic fibrosis features (CF) in High resolution computed tomography (HRCT) Scans. The aim of this study lies in presenting this system as a decision support tool for radiologists in future. The CF features t...

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Main Authors: Chaudhuri Tanusree, Gong Bo, Krueger-Ziolek Sabine, Schullcke Benjamin, Moeller Knut
Format: Article
Language:English
Published: De Gruyter 2016-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2016-0115
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author Chaudhuri Tanusree
Gong Bo
Krueger-Ziolek Sabine
Schullcke Benjamin
Moeller Knut
author_facet Chaudhuri Tanusree
Gong Bo
Krueger-Ziolek Sabine
Schullcke Benjamin
Moeller Knut
author_sort Chaudhuri Tanusree
collection DOAJ
description This paper describes a prototype of an automatic system for the detection and evaluation of Cystic fibrosis features (CF) in High resolution computed tomography (HRCT) Scans. The aim of this study lies in presenting this system as a decision support tool for radiologists in future. The CF features that have been detected and evaluated are Bronchiectasis and Mucus Plugging. This system recognizes Bronchiectasis as the presence of enlarged airways in pulmonary CF-CT slices whereas, Mucus Plugging has been recognized as clusters of high attenuation pixels. The dataset of this study consists of HRCT Scans of five CF patients of varying disease stages. Mean percentages of these CF features that were computed for each intercostal space, starting from the first to the fifth, fairly accurately match the different stages of the disease.
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spelling doaj.art-dfbc86e103a64bd2a69eac929cd632cb2022-12-21T21:46:09ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042016-09-012151952210.1515/cdbme-2016-0115cdbme-2016-0115Automatic determination of lung features of CF patients in CT scansChaudhuri Tanusree0Gong Bo1Krueger-Ziolek Sabine2Schullcke Benjamin3Moeller Knut4Institute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, GermanyInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, GermanyInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, GermanyInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, GermanyInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, GermanyThis paper describes a prototype of an automatic system for the detection and evaluation of Cystic fibrosis features (CF) in High resolution computed tomography (HRCT) Scans. The aim of this study lies in presenting this system as a decision support tool for radiologists in future. The CF features that have been detected and evaluated are Bronchiectasis and Mucus Plugging. This system recognizes Bronchiectasis as the presence of enlarged airways in pulmonary CF-CT slices whereas, Mucus Plugging has been recognized as clusters of high attenuation pixels. The dataset of this study consists of HRCT Scans of five CF patients of varying disease stages. Mean percentages of these CF features that were computed for each intercostal space, starting from the first to the fifth, fairly accurately match the different stages of the disease.https://doi.org/10.1515/cdbme-2016-01152d airway segmentationcomputed tomographycystic fibrosislung segmentationmucus plugging
spellingShingle Chaudhuri Tanusree
Gong Bo
Krueger-Ziolek Sabine
Schullcke Benjamin
Moeller Knut
Automatic determination of lung features of CF patients in CT scans
Current Directions in Biomedical Engineering
2d airway segmentation
computed tomography
cystic fibrosis
lung segmentation
mucus plugging
title Automatic determination of lung features of CF patients in CT scans
title_full Automatic determination of lung features of CF patients in CT scans
title_fullStr Automatic determination of lung features of CF patients in CT scans
title_full_unstemmed Automatic determination of lung features of CF patients in CT scans
title_short Automatic determination of lung features of CF patients in CT scans
title_sort automatic determination of lung features of cf patients in ct scans
topic 2d airway segmentation
computed tomography
cystic fibrosis
lung segmentation
mucus plugging
url https://doi.org/10.1515/cdbme-2016-0115
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