Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data

Here, the authors present Sparse Estimation of Correlations among Microbiomes (SECOM), a tool devised to characterize both linear and nonlinear relationships in microbiome data. When applied to human skin and infant gut microbiome data, SECOM is able to retrieve taxa interactions undescribed by prev...

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Main Authors: Huang Lin, Merete Eggesbø, Shyamal Das Peddada
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32243-x
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author Huang Lin
Merete Eggesbø
Shyamal Das Peddada
author_facet Huang Lin
Merete Eggesbø
Shyamal Das Peddada
author_sort Huang Lin
collection DOAJ
description Here, the authors present Sparse Estimation of Correlations among Microbiomes (SECOM), a tool devised to characterize both linear and nonlinear relationships in microbiome data. When applied to human skin and infant gut microbiome data, SECOM is able to retrieve taxa interactions undescribed by previous methods.
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spelling doaj.art-dfca4af60b984a4a9fb0fbf66d366e4f2022-12-22T01:36:29ZengNature PortfolioNature Communications2041-17232022-08-0113111610.1038/s41467-022-32243-xLinear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome dataHuang Lin0Merete Eggesbø1Shyamal Das Peddada2Biostatistics and Bioinformatics Branch, Eunice Shriver Kennedy NICHD, NIHNorwegian Institute of Public HealthBiostatistics and Bioinformatics Branch, Eunice Shriver Kennedy NICHD, NIHHere, the authors present Sparse Estimation of Correlations among Microbiomes (SECOM), a tool devised to characterize both linear and nonlinear relationships in microbiome data. When applied to human skin and infant gut microbiome data, SECOM is able to retrieve taxa interactions undescribed by previous methods.https://doi.org/10.1038/s41467-022-32243-x
spellingShingle Huang Lin
Merete Eggesbø
Shyamal Das Peddada
Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
Nature Communications
title Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
title_full Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
title_fullStr Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
title_full_unstemmed Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
title_short Linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
title_sort linear and nonlinear correlation estimators unveil undescribed taxa interactions in microbiome data
url https://doi.org/10.1038/s41467-022-32243-x
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AT shyamaldaspeddada linearandnonlinearcorrelationestimatorsunveilundescribedtaxainteractionsinmicrobiomedata