Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques
Important forensic diagnostic indicators of sudden death in coronary atherosclerotic heart disease, such as acute or chronic myocardial ischemic changes, sometimes make it difficult to locate the ischemic site due to the short death process, the lack of tissue reaction time. In some cases, the decea...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Forensic Medicine
2024-02-01
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| Series: | Fayixue Zazhi |
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| Online Access: | http://www.fyxzz.cn/fileup/1004-5619/PDF/2022.421203.pdf |
| _version_ | 1797257574848921600 |
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| author | Yun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN |
| author_facet | Yun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN |
| author_sort | Yun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN |
| collection | DOAJ |
| description | Important forensic diagnostic indicators of sudden death in coronary atherosclerotic heart disease, such as acute or chronic myocardial ischemic changes, sometimes make it difficult to locate the ischemic site due to the short death process, the lack of tissue reaction time. In some cases, the deceased died of sudden death on the first-episode, resulting in difficulty for medical examiners to make an accurate diagnosis. However, clinical studies on coronary instability plaque revealed the key role of coronary spasm and thrombosis caused by their lesions in sudden coronary death process. This paper mainly summarizes the pathological characteristics of unstable coronary plaque based on clinical medical research, including plaque rupture, plaque erosion and calcified nodules, as well as the influencing factors leading to plaque instability, and briefly describes the research progress and technique of the atherosclerotic plaques, in order to improve the study on the mechanism of sudden coronary death and improve the accuracy of the forensic diagnosis of sudden coronary death by diagnosing different pathologic states of coronary atherosclerotic plaques. |
| first_indexed | 2024-04-24T22:39:49Z |
| format | Article |
| id | doaj.art-dfca66d7bccd4222af95f63ce00eb35e |
| institution | Directory Open Access Journal |
| issn | 1004-5619 |
| language | zho |
| last_indexed | 2024-04-24T22:39:49Z |
| publishDate | 2024-02-01 |
| publisher | Editorial Office of Journal of Forensic Medicine |
| record_format | Article |
| series | Fayixue Zazhi |
| spelling | doaj.art-dfca66d7bccd4222af95f63ce00eb35e2024-03-19T06:48:44ZzhoEditorial Office of Journal of Forensic MedicineFayixue Zazhi1004-56192024-02-01401596310.12116/j.issn.1004-5619.2022.421203Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic PlaquesYun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN01.School of Forensic Medicine, Shanxi Medical University, Jinzhong 030600, Shanxi Province, China;2.Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China;3.Judical Appraisal Center of Shanxi Medical University, Jinzhong 030600, Shanxi Province, ChinaImportant forensic diagnostic indicators of sudden death in coronary atherosclerotic heart disease, such as acute or chronic myocardial ischemic changes, sometimes make it difficult to locate the ischemic site due to the short death process, the lack of tissue reaction time. In some cases, the deceased died of sudden death on the first-episode, resulting in difficulty for medical examiners to make an accurate diagnosis. However, clinical studies on coronary instability plaque revealed the key role of coronary spasm and thrombosis caused by their lesions in sudden coronary death process. This paper mainly summarizes the pathological characteristics of unstable coronary plaque based on clinical medical research, including plaque rupture, plaque erosion and calcified nodules, as well as the influencing factors leading to plaque instability, and briefly describes the research progress and technique of the atherosclerotic plaques, in order to improve the study on the mechanism of sudden coronary death and improve the accuracy of the forensic diagnosis of sudden coronary death by diagnosing different pathologic states of coronary atherosclerotic plaques.http://www.fyxzz.cn/fileup/1004-5619/PDF/2022.421203.pdf|forensic pathology|sudden cardiac death|coronary artery atherosclerotic heart disease|atheromatous plaques|pathological characteristics|review |
| spellingShingle | Yun-hong XING, Yang LI, Wen-zheng WANG, Liang-liang WANG, Le-le SUN, Qiu-xiang DU, Jie CAO, Guang-long HE, Jun-hong SUN Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques Fayixue Zazhi |forensic pathology|sudden cardiac death|coronary artery atherosclerotic heart disease|atheromatous plaques|pathological characteristics|review |
| title | Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques |
| title_full | Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques |
| title_fullStr | Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques |
| title_full_unstemmed | Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques |
| title_short | Pathological Characteristics and Classification of Unstable Coronary Atherosclerotic Plaques |
| title_sort | pathological characteristics and classification of unstable coronary atherosclerotic plaques |
| topic | |forensic pathology|sudden cardiac death|coronary artery atherosclerotic heart disease|atheromatous plaques|pathological characteristics|review |
| url | http://www.fyxzz.cn/fileup/1004-5619/PDF/2022.421203.pdf |
| work_keys_str_mv | AT yunhongxingyangliwenzhengwangliangliangwanglelesunqiuxiangdujiecaoguanglonghejunhongsun pathologicalcharacteristicsandclassificationofunstablecoronaryatheroscleroticplaques |