Impressive response to oral metronomic chemotherapy in ovarian cancer
Ovarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Elsevier
2022-12-01
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Series: | Current Problems in Cancer: Case Reports |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2666621922000618 |
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author | Dinesh Shet Rohan Chandra Gatty |
author_facet | Dinesh Shet Rohan Chandra Gatty |
author_sort | Dinesh Shet |
collection | DOAJ |
description | Ovarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in recurrent ovarian cancer, many patients die from disease progression. Despite the availability of PARP inhibitors in the maintenance setting, high costs make this out of reach of many deserving patients. Oral metronomic chemotherapy might be reasonable cheaper alternative for patients who cannot afford the standard treatment given the promising and hypothesis-generating results from this case series. |
first_indexed | 2024-04-12T02:24:55Z |
format | Article |
id | doaj.art-dfcc6903305d4baaa7481621348c88f5 |
institution | Directory Open Access Journal |
issn | 2666-6219 |
language | English |
last_indexed | 2024-04-12T02:24:55Z |
publishDate | 2022-12-01 |
publisher | Elsevier |
record_format | Article |
series | Current Problems in Cancer: Case Reports |
spelling | doaj.art-dfcc6903305d4baaa7481621348c88f52022-12-22T03:52:02ZengElsevierCurrent Problems in Cancer: Case Reports2666-62192022-12-018100197Impressive response to oral metronomic chemotherapy in ovarian cancerDinesh Shet0Rohan Chandra Gatty1Corresponding author.; Consultant Medical Oncologist, Father Muller Medical College, Mangalore, Karnataka, IndiaConsultant Medical Oncologist, Father Muller Medical College, Mangalore, Karnataka, IndiaOvarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in recurrent ovarian cancer, many patients die from disease progression. Despite the availability of PARP inhibitors in the maintenance setting, high costs make this out of reach of many deserving patients. Oral metronomic chemotherapy might be reasonable cheaper alternative for patients who cannot afford the standard treatment given the promising and hypothesis-generating results from this case series.http://www.sciencedirect.com/science/article/pii/S2666621922000618Ovarian cancerOral metronomic chemotherapy |
spellingShingle | Dinesh Shet Rohan Chandra Gatty Impressive response to oral metronomic chemotherapy in ovarian cancer Current Problems in Cancer: Case Reports Ovarian cancer Oral metronomic chemotherapy |
title | Impressive response to oral metronomic chemotherapy in ovarian cancer |
title_full | Impressive response to oral metronomic chemotherapy in ovarian cancer |
title_fullStr | Impressive response to oral metronomic chemotherapy in ovarian cancer |
title_full_unstemmed | Impressive response to oral metronomic chemotherapy in ovarian cancer |
title_short | Impressive response to oral metronomic chemotherapy in ovarian cancer |
title_sort | impressive response to oral metronomic chemotherapy in ovarian cancer |
topic | Ovarian cancer Oral metronomic chemotherapy |
url | http://www.sciencedirect.com/science/article/pii/S2666621922000618 |
work_keys_str_mv | AT dineshshet impressiveresponsetooralmetronomicchemotherapyinovariancancer AT rohanchandragatty impressiveresponsetooralmetronomicchemotherapyinovariancancer |