Impressive response to oral metronomic chemotherapy in ovarian cancer

Ovarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in...

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Main Authors: Dinesh Shet, Rohan Chandra Gatty
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Current Problems in Cancer: Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666621922000618
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author Dinesh Shet
Rohan Chandra Gatty
author_facet Dinesh Shet
Rohan Chandra Gatty
author_sort Dinesh Shet
collection DOAJ
description Ovarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in recurrent ovarian cancer, many patients die from disease progression. Despite the availability of PARP inhibitors in the maintenance setting, high costs make this out of reach of many deserving patients. Oral metronomic chemotherapy might be reasonable cheaper alternative for patients who cannot afford the standard treatment given the promising and hypothesis-generating results from this case series.
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spelling doaj.art-dfcc6903305d4baaa7481621348c88f52022-12-22T03:52:02ZengElsevierCurrent Problems in Cancer: Case Reports2666-62192022-12-018100197Impressive response to oral metronomic chemotherapy in ovarian cancerDinesh Shet0Rohan Chandra Gatty1Corresponding author.; Consultant Medical Oncologist, Father Muller Medical College, Mangalore, Karnataka, IndiaConsultant Medical Oncologist, Father Muller Medical College, Mangalore, Karnataka, IndiaOvarian cancer detected in late stages due to early no symptoms or vague symptoms and hence recurrence is rule in majority of patients. Treatment of recurrent disease is based on whether patient had platinum sensitive or platinum refractory disease. Despite various chemotherapy options available in recurrent ovarian cancer, many patients die from disease progression. Despite the availability of PARP inhibitors in the maintenance setting, high costs make this out of reach of many deserving patients. Oral metronomic chemotherapy might be reasonable cheaper alternative for patients who cannot afford the standard treatment given the promising and hypothesis-generating results from this case series.http://www.sciencedirect.com/science/article/pii/S2666621922000618Ovarian cancerOral metronomic chemotherapy
spellingShingle Dinesh Shet
Rohan Chandra Gatty
Impressive response to oral metronomic chemotherapy in ovarian cancer
Current Problems in Cancer: Case Reports
Ovarian cancer
Oral metronomic chemotherapy
title Impressive response to oral metronomic chemotherapy in ovarian cancer
title_full Impressive response to oral metronomic chemotherapy in ovarian cancer
title_fullStr Impressive response to oral metronomic chemotherapy in ovarian cancer
title_full_unstemmed Impressive response to oral metronomic chemotherapy in ovarian cancer
title_short Impressive response to oral metronomic chemotherapy in ovarian cancer
title_sort impressive response to oral metronomic chemotherapy in ovarian cancer
topic Ovarian cancer
Oral metronomic chemotherapy
url http://www.sciencedirect.com/science/article/pii/S2666621922000618
work_keys_str_mv AT dineshshet impressiveresponsetooralmetronomicchemotherapyinovariancancer
AT rohanchandragatty impressiveresponsetooralmetronomicchemotherapyinovariancancer