Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection

Abstract Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. This review summarizes the pathogenesis and significance of serological and molecular-based assays and new methods in the diagnosis and management of HCV infection after reading...

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Main Authors: Abbas Morovvati, somayeh dehghani sanij, Ashkan Dirbaziyan, homa Azadegan, shima Aghaei, hasan vahidi emami
Format: Article
Language:fas
Published: Qom Islamic Azad University 2019-08-01
Series:بیولوژی کاربردی
Subjects:
Online Access:https://sjoapb.qom.iau.ir/article_669340_359b40dac73b31adf27293495fad02ab.pdf
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author Abbas Morovvati
somayeh dehghani sanij
Ashkan Dirbaziyan
homa Azadegan
shima Aghaei
hasan vahidi emami
author_facet Abbas Morovvati
somayeh dehghani sanij
Ashkan Dirbaziyan
homa Azadegan
shima Aghaei
hasan vahidi emami
author_sort Abbas Morovvati
collection DOAJ
description Abstract Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. This review summarizes the pathogenesis and significance of serological and molecular-based assays and new methods in the diagnosis and management of HCV infection after reading this article, readers should be able to describe laboratory tests used in the diagnosis and management of HCV infection. They should also be able to describe the general principles for selecting the most appropriate laboratory test for diagnosis, therapeutic decision making, and assessment of virologic response to therapy. New methods for diagnosis of HCV virus infection could help for HCV detection and virus Genotypes in patient. Molecular methods are very sensitive and specific for RNA diagnosis and uses of this test for HCV genotypes Because HCV genotypes different response to druges.HCV genotypes detection could help for follow up treatment by interferon of patient. Keywords: hepatitis C virus, hepatitis, hepatocellular carcinoma, molecular diagnostics
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spelling doaj.art-dfcd9c6ddbec4b8a88509775f5d17d4c2023-07-17T14:57:28ZfasQom Islamic Azad Universityبیولوژی کاربردی2538-34342019-08-019345366669340Review on Laboratory tests for Diagnosis of Hepatitis C Virus InfectionAbbas Morovvati0somayeh dehghani sanij1Ashkan Dirbaziyan2homa Azadegan3shima Aghaei4hasan vahidi emami5management and teacherAria azma laboratory managmentLecture, Phd students in Microbiology, Department of microbiology, Qom Branch, Islamic Azad University, Qom, Iran.student, MS in Microbiology, Department of microbiology, Qom Branch, Islamic Azad University, Qom, Iran.student, MS in Microbiology, Department of microbiology, Qom Branch, Islamic Azad University, Qom, Iran.Lecture, MsC in Microbiology, Department of microbiology, Qom Branch, Islamic Azad University, Qom, Iran.Abstract Hepatitis C virus (HCV) infection is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. This review summarizes the pathogenesis and significance of serological and molecular-based assays and new methods in the diagnosis and management of HCV infection after reading this article, readers should be able to describe laboratory tests used in the diagnosis and management of HCV infection. They should also be able to describe the general principles for selecting the most appropriate laboratory test for diagnosis, therapeutic decision making, and assessment of virologic response to therapy. New methods for diagnosis of HCV virus infection could help for HCV detection and virus Genotypes in patient. Molecular methods are very sensitive and specific for RNA diagnosis and uses of this test for HCV genotypes Because HCV genotypes different response to druges.HCV genotypes detection could help for follow up treatment by interferon of patient. Keywords: hepatitis C virus, hepatitis, hepatocellular carcinoma, molecular diagnosticshttps://sjoapb.qom.iau.ir/article_669340_359b40dac73b31adf27293495fad02ab.pdfhepatitis c virushepatitishepatocellular carcinomamolecular diagnostics
spellingShingle Abbas Morovvati
somayeh dehghani sanij
Ashkan Dirbaziyan
homa Azadegan
shima Aghaei
hasan vahidi emami
Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
بیولوژی کاربردی
hepatitis c virus
hepatitis
hepatocellular carcinoma
molecular diagnostics
title Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
title_full Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
title_fullStr Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
title_full_unstemmed Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
title_short Review on Laboratory tests for Diagnosis of Hepatitis C Virus Infection
title_sort review on laboratory tests for diagnosis of hepatitis c virus infection
topic hepatitis c virus
hepatitis
hepatocellular carcinoma
molecular diagnostics
url https://sjoapb.qom.iau.ir/article_669340_359b40dac73b31adf27293495fad02ab.pdf
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AT ashkandirbaziyan reviewonlaboratorytestsfordiagnosisofhepatitiscvirusinfection
AT homaazadegan reviewonlaboratorytestsfordiagnosisofhepatitiscvirusinfection
AT shimaaghaei reviewonlaboratorytestsfordiagnosisofhepatitiscvirusinfection
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