Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria
The fungal genus Paecilomyces comprises numerous pathogenic and saprobic species, which are regularly isolated from insects, nematodes, soil, air, food, paper and many other materials. Some of the Paecilomyces species have been known to exhibit capabilities for curing human diseases. Here, bioactivi...
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| Format: | Article |
| Language: | English |
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University of Tarbiat Modares
2016-09-01
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| Series: | Journal of Crop Protection |
| Subjects: | |
| Online Access: | http://jcp.modares.ac.ir/article-3-12010-en.html |
| _version_ | 1818212894097014784 |
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| author | Sima Mohammadi Jalal Soltani Khosro Piri |
| author_facet | Sima Mohammadi Jalal Soltani Khosro Piri |
| author_sort | Sima Mohammadi |
| collection | DOAJ |
| description | The fungal genus Paecilomyces comprises numerous pathogenic and saprobic species, which are regularly isolated from insects, nematodes, soil, air, food, paper and many other materials. Some of the Paecilomyces species have been known to exhibit capabilities for curing human diseases. Here, bioactivities of metabolites from some soil inhabitant and invertebrate pathogenic Paecilomyces species were explored against a panel of target prokaryotic and eukaryotic microorganisms. First, Petri plate assays indicated that all tested Paecilomyces species were capable of producing diffusible metabolites and volatile compounds with antifungal activities against Pyricularia oryzae and Saccharomyces cerevisiae. Subsequently, the metabolites of the Paecilomyces species were extracted and the growth inhibitory and antimitotic effects of extra-cellular metabolites were shown using the yeast S. cerevisiae as a model. Further research indicated some antibacterial activity of extra-cellular metabolites from Paecilomyces species against human pathogenic bacteria Staphylococcus aureus, Bacillus subtilis, Streptococcus pyogenes (G+) and Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi (G-). These findings indicate that the Paecilomyces species, either saprobic or pathogenic, have a strong arsenal of bioactive metabolites which show inhibitory or cytotoxic effects against other microorganisms, with a potential for application in agroforestry and medicine. |
| first_indexed | 2024-12-12T05:55:38Z |
| format | Article |
| id | doaj.art-dfcdcdfe1a5949fd8e1e3268a3702758 |
| institution | Directory Open Access Journal |
| issn | 2251-9041 2251-905X |
| language | English |
| last_indexed | 2024-12-12T05:55:38Z |
| publishDate | 2016-09-01 |
| publisher | University of Tarbiat Modares |
| record_format | Article |
| series | Journal of Crop Protection |
| spelling | doaj.art-dfcdcdfe1a5949fd8e1e3268a37027582022-12-22T00:35:35ZengUniversity of Tarbiat ModaresJournal of Crop Protection2251-90412251-905X2016-09-0153377387Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteriaSima Mohammadi0Jalal Soltani1Khosro Piri2 Department of Plant Biotechnology, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran. Department of Plant Protection, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran. Department of Plant Biotechnology, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran. The fungal genus Paecilomyces comprises numerous pathogenic and saprobic species, which are regularly isolated from insects, nematodes, soil, air, food, paper and many other materials. Some of the Paecilomyces species have been known to exhibit capabilities for curing human diseases. Here, bioactivities of metabolites from some soil inhabitant and invertebrate pathogenic Paecilomyces species were explored against a panel of target prokaryotic and eukaryotic microorganisms. First, Petri plate assays indicated that all tested Paecilomyces species were capable of producing diffusible metabolites and volatile compounds with antifungal activities against Pyricularia oryzae and Saccharomyces cerevisiae. Subsequently, the metabolites of the Paecilomyces species were extracted and the growth inhibitory and antimitotic effects of extra-cellular metabolites were shown using the yeast S. cerevisiae as a model. Further research indicated some antibacterial activity of extra-cellular metabolites from Paecilomyces species against human pathogenic bacteria Staphylococcus aureus, Bacillus subtilis, Streptococcus pyogenes (G+) and Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi (G-). These findings indicate that the Paecilomyces species, either saprobic or pathogenic, have a strong arsenal of bioactive metabolites which show inhibitory or cytotoxic effects against other microorganisms, with a potential for application in agroforestry and medicine.http://jcp.modares.ac.ir/article-3-12010-en.htmlpaecilomyces fumoroseuspaecilomyces lilacinuspaecilomyces variotiisecondary metabolitevolatile compoundsantifungalantibacterialantimitotic |
| spellingShingle | Sima Mohammadi Jalal Soltani Khosro Piri Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria Journal of Crop Protection paecilomyces fumoroseus paecilomyces lilacinus paecilomyces variotii secondary metabolite volatile compounds antifungal antibacterial antimitotic |
| title | Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria |
| title_full | Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria |
| title_fullStr | Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria |
| title_full_unstemmed | Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria |
| title_short | Soilborne and invertebrate pathogenic Paecilomyces species show activity against pathogenic fungi and bacteria |
| title_sort | soilborne and invertebrate pathogenic paecilomyces species show activity against pathogenic fungi and bacteria |
| topic | paecilomyces fumoroseus paecilomyces lilacinus paecilomyces variotii secondary metabolite volatile compounds antifungal antibacterial antimitotic |
| url | http://jcp.modares.ac.ir/article-3-12010-en.html |
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