Do Vitamin D Levels Affect Bone Mineral Density in Reproductive Women with Low Ferritin Levels?

Objective:Iron deficiency anemia (IDA) is common in reproductive women. 25-hydroxyvitamin D [25-(OH)D] deficiency is common in those with IDA. The study evaluated the effect of low ferritin on 25-(OH)D levels and bone mineral density (BMD).Materials and Methods:One hundred forty women (15-25 years,...

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Bibliographic Details
Main Authors: Hatice Hamarat, Göknur Yorulmaz, Ayşe Ekim Aydemir, Emel Örge Gönüllü, Ahmet Musmul, Sinem Gürcü
Format: Article
Language:English
Published: Galenos Yayinevi 2022-04-01
Series:Türk Osteoporoz Dergisi
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Online Access: http://www.turkosteoporozdergisi.org/archives/archive-detail/article-preview/do-vitamin-d-levels-affect-bone-mineral-density-in/51335
Description
Summary:Objective:Iron deficiency anemia (IDA) is common in reproductive women. 25-hydroxyvitamin D [25-(OH)D] deficiency is common in those with IDA. The study evaluated the effect of low ferritin on 25-(OH)D levels and bone mineral density (BMD).Materials and Methods:One hundred forty women (15-25 years, 25-35 years, 35-45 years, 3 groups) with ferritin level <15 ng/mL and a control group of 50 healthy women were included in the study. A vitamin D level of 25-(OH)D>30.0 ng/mL was sufficient, vitamin D deficiency was defined as 25-(OH)D≥20.0, <30.0 ng/mL. Vitamin D deficiency as 25-(OH)D<20 ng/mL. Severe vitamin D deficiency 25-(OH)D<10 ng/mL. Femoral neck and lumbar spine BMD were measured by dual-energy X-ray absorptiometry. For the diagnosis of BMD, a Z-score of <-2 was evaluated with “lower bone mineral density than expected” and “expected bone density for >-2 years of age.”Results:The mean ages of the patients and healthy controls were 34±10 and 29±9 years. Serum 25-(OH)D level was found to be low in the patient group (p<0.01). Low-intensity BMD was present in the low ferritin groups (p>0.05).Conclusion:Low vitamin D levels detected in reproductive women with anemia cause low BMD.
ISSN:2147-2653