Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution
The phase behavior of amphiphilic Pluronic block copolymers in aqueous solution is of importance for a broad spectrum of practical applications but has not been fully exploited yet. Here, the phase behavior of the mixture of the Pluronic P65 and P105 triblock copolymer, (which have the same composit...
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| Format: | Article |
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MDPI AG
2018-10-01
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| Series: | Micromachines |
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| Online Access: | http://www.mdpi.com/2072-666X/9/10/505 |
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| author | Jong-Dae Jang Eunhye Kim Min-Jae Lee Young-Soo Han Joona Bang Tae-Hwan Kim |
| author_facet | Jong-Dae Jang Eunhye Kim Min-Jae Lee Young-Soo Han Joona Bang Tae-Hwan Kim |
| author_sort | Jong-Dae Jang |
| collection | DOAJ |
| description | The phase behavior of amphiphilic Pluronic block copolymers in aqueous solution is of importance for a broad spectrum of practical applications but has not been fully exploited yet. Here, the phase behavior of the mixture of the Pluronic P65 and P105 triblock copolymer, (which have the same composition of PEO and PPO but the different molecular weight) and organic derivative, 5-methyl salicylic acid (5mS), in aqueous solution has been investigated by using small angle neutron scattering (SANS). According to the temperature and the 5mS concentration, SANS measurements showed that the P65-5mS mixtures sequentially transform into a random coil, sphere, vesicle, cylinder, and vesicle again, while the P105-5mS mixtures form spherical particles with two different sizes without any topological phase transition. Upon heating, the formation of two different kinds of the vesicle structure of amphiphilic block copolymer in aqueous solution is very unusual. This phase behavior was explained as the coupled effect of the simultaneous increase of the hydrophobicity of the polymer and the solubility of 5mS molecules upon heating. This result gives fundamental information for the practical use of Pluronic polymers in nano- and bio-science and it provides a simple route for the fabrication of the nanostructure without a complicated procedure. |
| first_indexed | 2024-12-22T01:29:38Z |
| format | Article |
| id | doaj.art-dfd2f1efcc1d47d5892ac3ea6669f120 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-12-22T01:29:38Z |
| publishDate | 2018-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-dfd2f1efcc1d47d5892ac3ea6669f1202022-12-21T18:43:31ZengMDPI AGMicromachines2072-666X2018-10-0191050510.3390/mi9100505mi9100505Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous SolutionJong-Dae Jang0Eunhye Kim1Min-Jae Lee2Young-Soo Han3Joona Bang4Tae-Hwan Kim5Neutron Science Division, Research Reactor Utilization Department, Korea Atomic Energy Research Institute, 1045 Daedeok-daero, Yuseong-gu, Daejeon 34057, KoreaNeutron Science Division, Research Reactor Utilization Department, Korea Atomic Energy Research Institute, 1045 Daedeok-daero, Yuseong-gu, Daejeon 34057, KoreaDepartment of Nuclear and Quantum Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, KoreaNeutron Science Division, Research Reactor Utilization Department, Korea Atomic Energy Research Institute, 1045 Daedeok-daero, Yuseong-gu, Daejeon 34057, KoreaDepartment of Chemical and Biological Engineering, Korea University, 145 Anam-ro, Sungbuk-gu, Seoul 02841, KoreaNeutron Science Division, Research Reactor Utilization Department, Korea Atomic Energy Research Institute, 1045 Daedeok-daero, Yuseong-gu, Daejeon 34057, KoreaThe phase behavior of amphiphilic Pluronic block copolymers in aqueous solution is of importance for a broad spectrum of practical applications but has not been fully exploited yet. Here, the phase behavior of the mixture of the Pluronic P65 and P105 triblock copolymer, (which have the same composition of PEO and PPO but the different molecular weight) and organic derivative, 5-methyl salicylic acid (5mS), in aqueous solution has been investigated by using small angle neutron scattering (SANS). According to the temperature and the 5mS concentration, SANS measurements showed that the P65-5mS mixtures sequentially transform into a random coil, sphere, vesicle, cylinder, and vesicle again, while the P105-5mS mixtures form spherical particles with two different sizes without any topological phase transition. Upon heating, the formation of two different kinds of the vesicle structure of amphiphilic block copolymer in aqueous solution is very unusual. This phase behavior was explained as the coupled effect of the simultaneous increase of the hydrophobicity of the polymer and the solubility of 5mS molecules upon heating. This result gives fundamental information for the practical use of Pluronic polymers in nano- and bio-science and it provides a simple route for the fabrication of the nanostructure without a complicated procedure.http://www.mdpi.com/2072-666X/9/10/505block copolymerself-assemblynanostructuresphase behaviorsmall angle neutron scattering (SANS) |
| spellingShingle | Jong-Dae Jang Eunhye Kim Min-Jae Lee Young-Soo Han Joona Bang Tae-Hwan Kim Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution Micromachines block copolymer self-assembly nanostructures phase behavior small angle neutron scattering (SANS) |
| title | Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution |
| title_full | Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution |
| title_fullStr | Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution |
| title_full_unstemmed | Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution |
| title_short | Unexpected Phase Behavior of Pluronic Polymer-Organic Derivative Mixtures Depending on Temperature in Aqueous Solution |
| title_sort | unexpected phase behavior of pluronic polymer organic derivative mixtures depending on temperature in aqueous solution |
| topic | block copolymer self-assembly nanostructures phase behavior small angle neutron scattering (SANS) |
| url | http://www.mdpi.com/2072-666X/9/10/505 |
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