Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration

Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a major cause of blindness. Recent studies have reported impaired glycolysis in AMD patients with a high lactate/pyruvate ratio. Elevated homocysteine (Hcy) (Hyperhomocysteinemia, HHcy) was observed in several clinical studies, reporting an association betwe...

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Bibliographic Details
Main Authors:	Yara A. Samra, Yusra Zaidi, Pragya Rajpurohit, Raju Raghavan, Lun Cai, Ismail Kaddour-Djebbar, Amany Tawfik
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	International Journal of Molecular Sciences
Subjects:	N-methyl-D-aspartate receptor homocysteine age-related macular degeneration blood retinal barrier cystathionine-β—synthase mouse
Online Access:	https://www.mdpi.com/1422-0067/24/2/1071

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