Orofacial Granulomatosis: Case Report

An 18-year-old girl was referred to the Department of Oral Medicine with upper lip swelling. She was in good general health and laboratory tests were within the normal range. Histopathologic diagnosis did not reveal the presence of granulomas. This is consistent with the finding that 30% of patients...

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Main Authors: Vlaho Brailo, Sven Seiwert, Vedran Tomašić, Iva Bakale, Danica Vidović Juras, Suzana Ljubojević Hadžavdić, Vanja Vučićević Boras
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2015-01-01
Series:Acta Clinica Croatica
Subjects:
Online Access:http://hrcak.srce.hr/file/219306
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author Vlaho Brailo
Sven Seiwert
Vedran Tomašić
Iva Bakale
Danica Vidović Juras
Suzana Ljubojević Hadžavdić
Vanja Vučićević Boras
author_facet Vlaho Brailo
Sven Seiwert
Vedran Tomašić
Iva Bakale
Danica Vidović Juras
Suzana Ljubojević Hadžavdić
Vanja Vučićević Boras
author_sort Vlaho Brailo
collection DOAJ
description An 18-year-old girl was referred to the Department of Oral Medicine with upper lip swelling. She was in good general health and laboratory tests were within the normal range. Histopathologic diagnosis did not reveal the presence of granulomas. This is consistent with the finding that 30% of patients with orofacial granulomatosis do not have granulomas on their biopsies. The patient was treated with intralesional steroids once a week for three weeks. The lesion subsided, but not completely, and recurred partially after ketchup intake. This case report highlights the fact that in every patient with non-odontogenic facial or oral swelling, systemic diseases such as sarcoidosis, Crohn’s disease, tuberculosis, etc. must be excluded. Furthermore, it is not unusual that in patients with orofacial granulomatosis, noncaseating granulomas are absent in the histopathologic finding.
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spelling doaj.art-dfd4e72437a04ebbb4cd458588d9f62d2022-12-21T23:32:15ZengSestre Milosrdnice University hospital, Institute of Clinical Medical ResearchActa Clinica Croatica0353-94661333-94512015-01-0154.3.378380Orofacial Granulomatosis: Case ReportVlaho Brailo0Sven Seiwert1Vedran Tomašić2Iva Bakale3Danica Vidović Juras4Suzana Ljubojević Hadžavdić5Vanja Vučićević Boras6Department of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Pathology, Zagreb University Hospital Center; Zagreb, Croatia; School of Medicine, University of Zagreb, Zagreb, CroatiaClinical Department of Gastroenterology, Sestre milosrdnice University Hospital Center, Zagreb, CroatiaDepartment of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, CroatiaClinical Department of Dermatology and Venereology, Zagreb University Hospital Center, Zagreb, CroatiaDepartment of Oral medicine, School of Dental Medicine, University of Zagreb and Zagreb University Hospital Center, Zagreb, CroatiaAn 18-year-old girl was referred to the Department of Oral Medicine with upper lip swelling. She was in good general health and laboratory tests were within the normal range. Histopathologic diagnosis did not reveal the presence of granulomas. This is consistent with the finding that 30% of patients with orofacial granulomatosis do not have granulomas on their biopsies. The patient was treated with intralesional steroids once a week for three weeks. The lesion subsided, but not completely, and recurred partially after ketchup intake. This case report highlights the fact that in every patient with non-odontogenic facial or oral swelling, systemic diseases such as sarcoidosis, Crohn’s disease, tuberculosis, etc. must be excluded. Furthermore, it is not unusual that in patients with orofacial granulomatosis, noncaseating granulomas are absent in the histopathologic finding.http://hrcak.srce.hr/file/219306Granulomatosis, orofacial – diagnosisGranulomatosis, orofacial – therapyCase reports
spellingShingle Vlaho Brailo
Sven Seiwert
Vedran Tomašić
Iva Bakale
Danica Vidović Juras
Suzana Ljubojević Hadžavdić
Vanja Vučićević Boras
Orofacial Granulomatosis: Case Report
Acta Clinica Croatica
Granulomatosis, orofacial – diagnosis
Granulomatosis, orofacial – therapy
Case reports
title Orofacial Granulomatosis: Case Report
title_full Orofacial Granulomatosis: Case Report
title_fullStr Orofacial Granulomatosis: Case Report
title_full_unstemmed Orofacial Granulomatosis: Case Report
title_short Orofacial Granulomatosis: Case Report
title_sort orofacial granulomatosis case report
topic Granulomatosis, orofacial – diagnosis
Granulomatosis, orofacial – therapy
Case reports
url http://hrcak.srce.hr/file/219306
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AT suzanaljubojevichadzavdic orofacialgranulomatosiscasereport
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