The molecular regulatory mechanisms of meiotic arrest and resumption in Oocyte development and maturation

Abstract In human female primordial germ cells, the transition from mitosis to meiosis begins from the fetal stage. In germ cells, meiosis is arrested at the diplotene stage of prophase in meiosis I (MI) after synapsis and recombination of homologous chromosomes, which cannot be segregated. Within t...

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Bibliographic Details
Main Authors: Zhenle Pei, Ke Deng, Congjian Xu, Shuo Zhang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Online Access:https://doi.org/10.1186/s12958-023-01143-0