Non-CpG Oligonucleotides Exert Adjuvant Effects by Enhancing Cognate B Cell-T Cell Interactions, Leading to B Cell Activation, Differentiation, and Isotype Switching

Natural and synthetic nucleic acids are known to exert immunomodulatory properties. Notably, nucleic acids are known to modulate immune function via several different pathways and various cell types, necessitating a complex interpretation of their effects. In this study we set out to compare the eff...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Melinda Herbáth, Krisztián Papp, Anna Erdei, József Prechl
Format: Artikel
Sprache:English
Veröffentlicht: Hindawi Limited 2015-01-01
Schriftenreihe:Journal of Immunology Research
Online Zugang:http://dx.doi.org/10.1155/2015/340468