A novel peptide thrombopoietin mimetic designing and optimization using computational approach

A novel peptide thrombopoietin mimetic designing and optimization using computational approach

Thrombopoietin receptor (TPOR) is a cytokine receptor protein; activation of cell surface TPOR by thrombopoietin (TPO) triggers an intracellular cascade of megakaryocytopoiesis for the formation of platelets. TPO is a glycoprotein hormone which stimulates megakaryocytes formation and maturation to p...

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Bibliographic Details
Main Authors: Vimal kishor Singh, Neeraj Kumar, Manisha Kalsan, Abhishek Saini, Ramesh Chandra
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Thrombopoietin
molecular docking
molecular dynamics simulation.
Thrombopoietin receptor
Mimetic Library Designing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2016.00069/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fbioe.2016.00069/full

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