A novel peptide thrombopoietin mimetic designing and optimization using computational approach
Thrombopoietin receptor (TPOR) is a cytokine receptor protein; activation of cell surface TPOR by thrombopoietin (TPO) triggers an intracellular cascade of megakaryocytopoiesis for the formation of platelets. TPO is a glycoprotein hormone which stimulates megakaryocytes formation and maturation to p...
Main Authors: | Vimal kishor Singh, Neeraj Kumar, Manisha Kalsan, Abhishek Saini, Ramesh Chandra |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-08-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fbioe.2016.00069/full |
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