Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal
Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It...
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| Format: | Article |
| Language: | English |
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Nobel Medical College Teaching Hospital
2023-07-01
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| Series: | Journal of Nobel Medical College |
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| Online Access: | https://www.nepjol.info/index.php/JoNMC/article/view/56340 |
| _version_ | 1797771396028301312 |
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| author | Kewal Shrestha Prabhat Kumar Singh Kumari Ragani Yadav Ganesh Kumar Singh |
| author_facet | Kewal Shrestha Prabhat Kumar Singh Kumari Ragani Yadav Ganesh Kumar Singh |
| author_sort | Kewal Shrestha |
| collection | DOAJ |
| description | Background: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity.
Materials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included.
Results: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens.
Conclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistance |
| first_indexed | 2024-03-12T21:35:56Z |
| format | Article |
| id | doaj.art-dfdca0d863204a2cac3e94b13c427db4 |
| institution | Directory Open Access Journal |
| issn | 2091-2331 2091-234X |
| language | English |
| last_indexed | 2024-03-12T21:35:56Z |
| publishDate | 2023-07-01 |
| publisher | Nobel Medical College Teaching Hospital |
| record_format | Article |
| series | Journal of Nobel Medical College |
| spelling | doaj.art-dfdca0d863204a2cac3e94b13c427db42023-07-27T07:18:31ZengNobel Medical College Teaching HospitalJournal of Nobel Medical College2091-23312091-234X2023-07-01121394410.3126/jonmc.v12i1.5634083440Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern NepalKewal Shrestha0https://orcid.org/0000-0002-3863-8283Prabhat Kumar Singh1Kumari Ragani Yadav2Ganesh Kumar Singh3Department of Microbiology, Nobel Medical College Teaching hospital, Biratnagar, NepalDepartment of Microbiology, Nobel Medical College Teaching hospital, Biratnagar, NepalDepartment of Microbiology, Nobel Medical College Teaching hospital, Biratnagar, NepalDepartment of Microbiology, Nobel Medical College Teaching hospital, Biratnagar, NepalBackground: Urinary tract infection (UTI) is defined as growth of micro-organisms >105 CFU/ml in mid-stream urine samples. [1] Globally, urinary tract infection is considered a major public health concern with the second most common bacterial infection affecting individuals of different ages. It is estimated that worldwide 150 million cases of UTI occur per year and bacteria are responsible for about 95% of all the cases with each year. [3, 4] This study was designed to describe the pattern of microorganisms causing UTI and their antibiotic sensitivity. Materials and Methods: This is a hospital based cross-sectional study conducted in the Department of Microbiology from January 2022 to June 2022 after taking ethical approval from Institutional Review Committee, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The patient profiles or records visiting a tertiary care hospital of both sex and every age group who were having symptoms and clinical diagnosis of urinary tract infection were included. Results: A total of 2247 urine samples were collected, 501(22.29%) of the urine sample yielded significant growth of uropathogenes. The most common bacteria was found to be Escherichia coli (E. coli) that accounts for 73.05% followed by Enterococcus species 11.57%, Klebsiella pneumoniae 8.98% and amikacin and nitrofurantoin was found to be the most sensitive antibiotic to gram negative uropathogens. Conclusion: The prevalence of uropathogenes was found to be higher in our study. Significant bacteriuria was seen in the female than male. The total number of patient with culture positivity was higher in younger age groups with high frequency of antibiotic resistancehttps://www.nepjol.info/index.php/JoNMC/article/view/56340antibiotic resistancefemaleurinary tract infection |
| spellingShingle | Kewal Shrestha Prabhat Kumar Singh Kumari Ragani Yadav Ganesh Kumar Singh Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal Journal of Nobel Medical College antibiotic resistance female urinary tract infection |
| title | Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal |
| title_full | Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal |
| title_fullStr | Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal |
| title_full_unstemmed | Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal |
| title_short | Prevalence and Antibiogram of Bacterial Uropathogens from a Tertiary Care Hospital of Eastern Nepal |
| title_sort | prevalence and antibiogram of bacterial uropathogens from a tertiary care hospital of eastern nepal |
| topic | antibiotic resistance female urinary tract infection |
| url | https://www.nepjol.info/index.php/JoNMC/article/view/56340 |
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