The significance of M1‐polarized CD163+ macrophages in acute graft‐versus‐host disease (GVHD): Possible mechanisms of GVHD in the development of skin lesions

The significance of M1‐polarized CD163+ macrophages in acute graft‐versus‐host disease (GVHD): Possible mechanisms of GVHD in the development of skin lesions

Abstract Objectives Graft‐versus‐host disease (GVHD) is an important complication of bone marrow transplantation. Recent reports suggest the significance of T‐cell subsets (Th1, Th17, and cytotoxic CD8+ T cells) as well as CD163+ macrophages in the development of cutaneous GVHD. CD163+ macrophages p...

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Bibliographic Details
Main Authors: Yusuke Muto, Taku Fujimura, Yumi Kambayashi, Kentaro Ohuchi, Chunbing Lyu, Hitoshi Terui, Masato Mizuashi, Setsuya Aiba, Yoshihide Asano
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Journal of Cutaneous Immunology and Allergy
Subjects:
CD163+ macrophages
GVHD
interferon‐inducible chemokines
pSTAT
Online Access:https://doi.org/10.1002/cia2.12304

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