Silencing PLOD2 attenuates cancer stem cell-like characteristics and cisplatin-resistant through Integrin β1 in laryngeal cancer

Silencing PLOD2 attenuates cancer stem cell-like characteristics and cisplatin-resistant through Integrin β1 in laryngeal cancer

Laryngeal cancer (LC) is an aggressive malignancy resistant to drug treatments. It has been postulated that cancer stem cells (CSCs) persist in a unique population of cancer cells involved in tumor progression and drug-resistance. In the present study, the effects of PLOD2 expression on ordinary and...

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Bibliographic Details
Main Authors: Meiyan Song, Xing Liu, Tao Li, Yueqin Zhang, Xiaoyan Zhao, Wen Sun, Zhen Li
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Translational Oncology
Subjects:
PLOD2
Integrin β1
Laryngeal cancer
Drug-resistance
Cancer stem cells
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332200119X

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