Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review

Background: The aim of this systematic review was to evaluate whether patients with gingival recession would benefit from an acellular dermal matrix graft (ADMG) in ways that are comparable to the gold standard of the subepithelial connective tissue graft (SCTG). Materials and Methods: A systematic...

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Main Authors: Sarah Ivy Gallagher, Debora Candace Matthews
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Indian Society of Periodontology
Subjects:
Online Access:http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=6;spage=439;epage=448;aulast=Gallagher
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author Sarah Ivy Gallagher
Debora Candace Matthews
author_facet Sarah Ivy Gallagher
Debora Candace Matthews
author_sort Sarah Ivy Gallagher
collection DOAJ
description Background: The aim of this systematic review was to evaluate whether patients with gingival recession would benefit from an acellular dermal matrix graft (ADMG) in ways that are comparable to the gold standard of the subepithelial connective tissue graft (SCTG). Materials and Methods: A systematic review and meta-analysis comparing ADMG to SCTG for the treatment of Miller Class I and II recession defects was conducted according to PRISMA guidelines. PubMed, Excerpta Medica Database, and Cochrane Central Register of Controlled Trials databases were searched up to March 2016 for controlled trials with minimum 6 months duration. The primary outcome was root coverage; secondary outcomes included attachment level change, keratinized tissue (KT) change, and patient-based outcomes. Both authors independently assessed the quality of each included trial and extracted the relevant data. Results: From 158 potential titles, 17 controlled trials were included in the meta-analysis. There were no differences between ADMG and SCTG for mean root coverage, percent root coverage, and clinical attachment level gain. ADMG was statistically better than SCTG for gain in width of KT (−0.43 mm; 95% confidence interval: −0.72, −0.15). Only one study compared patient-based outcomes. Conclusion: This review found that an ADMG would be a suitable root coverage substitute for an SCTG when avoidance of the second surgical site is preferred.
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spelling doaj.art-dfe1a3cd5ff2456aa4220f550f53c6f92022-12-22T03:07:39ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Periodontology0972-124X2017-01-0121643944810.4103/jisp.jisp_222_17Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic reviewSarah Ivy GallagherDebora Candace MatthewsBackground: The aim of this systematic review was to evaluate whether patients with gingival recession would benefit from an acellular dermal matrix graft (ADMG) in ways that are comparable to the gold standard of the subepithelial connective tissue graft (SCTG). Materials and Methods: A systematic review and meta-analysis comparing ADMG to SCTG for the treatment of Miller Class I and II recession defects was conducted according to PRISMA guidelines. PubMed, Excerpta Medica Database, and Cochrane Central Register of Controlled Trials databases were searched up to March 2016 for controlled trials with minimum 6 months duration. The primary outcome was root coverage; secondary outcomes included attachment level change, keratinized tissue (KT) change, and patient-based outcomes. Both authors independently assessed the quality of each included trial and extracted the relevant data. Results: From 158 potential titles, 17 controlled trials were included in the meta-analysis. There were no differences between ADMG and SCTG for mean root coverage, percent root coverage, and clinical attachment level gain. ADMG was statistically better than SCTG for gain in width of KT (−0.43 mm; 95% confidence interval: −0.72, −0.15). Only one study compared patient-based outcomes. Conclusion: This review found that an ADMG would be a suitable root coverage substitute for an SCTG when avoidance of the second surgical site is preferred.http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=6;spage=439;epage=448;aulast=GallagherAcellular dermisconnective tissuegingival recessionmeta-analysissystematic review
spellingShingle Sarah Ivy Gallagher
Debora Candace Matthews
Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
Journal of Indian Society of Periodontology
Acellular dermis
connective tissue
gingival recession
meta-analysis
systematic review
title Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
title_full Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
title_fullStr Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
title_full_unstemmed Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
title_short Acellular dermal matrix and subepithelial connective tissue grafts for root coverage: A systematic review
title_sort acellular dermal matrix and subepithelial connective tissue grafts for root coverage a systematic review
topic Acellular dermis
connective tissue
gingival recession
meta-analysis
systematic review
url http://www.jisponline.com/article.asp?issn=0972-124X;year=2017;volume=21;issue=6;spage=439;epage=448;aulast=Gallagher
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AT deboracandacematthews acellulardermalmatrixandsubepithelialconnectivetissuegraftsforrootcoverageasystematicreview