Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus
Systolic and diastolic blood pressures display a circadian rhythmicity that can be assessed by 24-hour ambulatory blood pressure monitoring and analysed using the cosinor procedure. Altered characteristics to the circadian rhythm of blood pressure, which may result in adverse health outcomes, have b...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2013-10-01
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| Series: | European Medical Journal Diabetes |
| Subjects: | |
| Online Access: | http://emjreviews.com/wp-content/uploads/Ambulatory-Blood-Pressure-Monitoring-and-Circadian-Rhythm-of-Blood-Pressure-in-Diabetes-Mellitus.pdf |
| _version_ | 1818993480714682368 |
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| author | Elena Matteucci Ottavio Giampietro |
| author_facet | Elena Matteucci Ottavio Giampietro |
| author_sort | Elena Matteucci |
| collection | DOAJ |
| description | Systolic and diastolic blood pressures display a circadian rhythmicity that can be assessed by 24-hour ambulatory blood pressure monitoring and analysed using the cosinor procedure. Altered characteristics to the circadian rhythm of blood pressure, which may result in adverse health outcomes, have been observed in both prediabetes and diabetes. We have investigated the circadian variability of blood pressure in patients with type 1 and type 2 diabetes. Chronobiologically interpreted ambulatory blood pressure monitoring uncovered not only midline estimating statistic of rhythm (MESOR)-hypertension and circadian hyper-amplitude-tension, but also circadian ecphasia (an odd timing of the daily blood pressure swing). Diastolic blood pressure acrophases were found to be phase shifted to earlier along the time axis only in patients with diabetes, but not in those with essential hypertension. Several mechanisms, from changes in nutrient-dependent signalling pathways to diabetic autonomic neuropathy, can contribute to alterations of circadian time structures in diabetic people. The chronology of blood pressure changes in animal models of diabetes and hypertension suggests that a chronobiological approach to the diagnosis of blood pressure disorders could offer advantages, but longitudinal studies in humans are needed to determine its potential relevance in hypertension associated with diabetes. |
| first_indexed | 2024-12-20T20:42:44Z |
| format | Article |
| id | doaj.art-dfe21a7bf46747fea2af7b8c247ce238 |
| institution | Directory Open Access Journal |
| issn | 2054-6181 |
| language | English |
| last_indexed | 2024-12-20T20:42:44Z |
| publishDate | 2013-10-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Diabetes |
| spelling | doaj.art-dfe21a7bf46747fea2af7b8c247ce2382022-12-21T19:27:07ZengEuropean Medical JournalEuropean Medical Journal Diabetes2054-61812013-10-01113843Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes MellitusElena Matteucci0Ottavio Giampietro1Dietology Unit, Department of Clinical and Experimental Medicine, Pisa University, ItalyDietology Unit, Department of Clinical and Experimental Medicine, Pisa University, ItalySystolic and diastolic blood pressures display a circadian rhythmicity that can be assessed by 24-hour ambulatory blood pressure monitoring and analysed using the cosinor procedure. Altered characteristics to the circadian rhythm of blood pressure, which may result in adverse health outcomes, have been observed in both prediabetes and diabetes. We have investigated the circadian variability of blood pressure in patients with type 1 and type 2 diabetes. Chronobiologically interpreted ambulatory blood pressure monitoring uncovered not only midline estimating statistic of rhythm (MESOR)-hypertension and circadian hyper-amplitude-tension, but also circadian ecphasia (an odd timing of the daily blood pressure swing). Diastolic blood pressure acrophases were found to be phase shifted to earlier along the time axis only in patients with diabetes, but not in those with essential hypertension. Several mechanisms, from changes in nutrient-dependent signalling pathways to diabetic autonomic neuropathy, can contribute to alterations of circadian time structures in diabetic people. The chronology of blood pressure changes in animal models of diabetes and hypertension suggests that a chronobiological approach to the diagnosis of blood pressure disorders could offer advantages, but longitudinal studies in humans are needed to determine its potential relevance in hypertension associated with diabetes.http://emjreviews.com/wp-content/uploads/Ambulatory-Blood-Pressure-Monitoring-and-Circadian-Rhythm-of-Blood-Pressure-in-Diabetes-Mellitus.pdfAcrophaseAmbulatory Blood Pressure MonitoringCircadian RhythmEssential HypertensionMidline Estimating Statistic of RhythmType 1 Diabetes MellitusType 2 Diabetes Mellitus |
| spellingShingle | Elena Matteucci Ottavio Giampietro Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus European Medical Journal Diabetes Acrophase Ambulatory Blood Pressure Monitoring Circadian Rhythm Essential Hypertension Midline Estimating Statistic of Rhythm Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus |
| title | Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus |
| title_full | Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus |
| title_fullStr | Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus |
| title_full_unstemmed | Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus |
| title_short | Ambulatory Blood Pressure Monitoring and Circadian Rhythm of Blood Pressure in Diabetes Mellitus |
| title_sort | ambulatory blood pressure monitoring and circadian rhythm of blood pressure in diabetes mellitus |
| topic | Acrophase Ambulatory Blood Pressure Monitoring Circadian Rhythm Essential Hypertension Midline Estimating Statistic of Rhythm Type 1 Diabetes Mellitus Type 2 Diabetes Mellitus |
| url | http://emjreviews.com/wp-content/uploads/Ambulatory-Blood-Pressure-Monitoring-and-Circadian-Rhythm-of-Blood-Pressure-in-Diabetes-Mellitus.pdf |
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