Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance

Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance

Tetradecylthioacetic acid (TTA) is a non-β-oxidizable fatty acid analog, which potently regulates lipid homeostasis. Here we evaluate the ability of TTA to prevent diet-induced and genetically determined adiposity and insulin resistance. In Wistar rats fed a high fat diet, TTA administration complet...

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Bibliographic Details
Main Authors: Lise Madsen, Michéle Guerre-Millo, Esben N. Flindt, Kjetil Berge, Karl Johan Tronstad, Elin Bergene, Elena Sebokova, Arild C. Rustan, Jørgen Jensen, Susanne Mandrup, Karsten Kristiansen, Iwar Klimes, Bart Staels, Rolf K. Berge
Format: Article
Language:English
Published: Elsevier 2002-05-01
Series:Journal of Lipid Research
Subjects:
fatty acid analogues
insulin action
fatty acid oxidation
PPAR
CPT-I
CPT-II
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301164

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