Immunoglobulin G is a natural oxytocin carrier which modulates oxytocin receptor signaling: relevance to aggressive behavior in humans

Immunoglobulin G is a natural oxytocin carrier which modulates oxytocin receptor signaling: relevance to aggressive behavior in humans

Abstract Oxytocin is a neuropeptide produced mainly in the hypothalamus and secreted in the CNS and blood. In the brain, it plays a major role in promoting social interactions. Here we show that in human plasma about 60% of oxytocin is naturally bound to IgG which modulates oxytocin receptor signali...

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Bibliographic Details
Main Authors: Henning Værøy, Emilie Lahaye, Christophe Dubessy, Magalie Benard, Marion Nicol, Yamina Cherifi, Saloua Takhlidjt, Jean-Luc do Rego, Jean-Claude do Rego, Nicolas Chartrel, Sergueï O. Fetissov
Format: Article
Language:English
Published: Springer 2023-10-01
Series:Discover Mental Health
Subjects:
Aggressive behavior
Neuroendocrinology
Neuropeptides
Oxytocin
Oxytocin receptor
Intracellular signaling
Online Access:https://doi.org/10.1007/s44192-023-00048-z

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