Rapid and simple LC–MS/MS determination of urinary ethyl glucuronide, naltrexone, 6β-naltrexol, chlordiazepoxide, and norchlordiazepoxide for monitoring alcohol abuse

Rapid and simple LC–MS/MS determination of urinary ethyl glucuronide, naltrexone, 6β-naltrexol, chlordiazepoxide, and norchlordiazepoxide for monitoring alcohol abuse

Abstract In this study, a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed to detect ethyl glucuronide (EtG), which is a biomarker for monitoring alcohol consumption, and naltrexone (NTX), 6β-naltrexol (6βNTX), chlordiazepoxide (CDP), and norchlordiazepoxide (norCDP), w...

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Bibliographic Details
Main Authors: Yeong Eun Sim, Ji Woo Kim, Beom Jun Ko, Jin Young Kim
Format: Article
Language:English
Published: SpringerOpen 2022-02-01
Series:Journal of Analytical Science and Technology
Subjects:
Alcohol abuse
Ethyl glucuronide
Naltrexone
Chlordiazepoxide
Urine
LC–MS/MS
Online Access:https://doi.org/10.1186/s40543-022-00315-8

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