AlphaFold2: A Role for Disordered Protein/Region Prediction?

AlphaFold2: A Role for Disordered Protein/Region Prediction?

The development of AlphaFold2 marked a paradigm-shift in the structural biology community. Herein, we assess the ability of AlphaFold2 to predict disordered regions against traditional sequence-based disorder predictors. We find that AlphaFold2 performs well at discriminating disordered regions, but...

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Bibliographic Details
Main Authors:	Carter J. Wilson, Wing-Yiu Choy, Mikko Karttunen
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	International Journal of Molecular Sciences
Subjects:	AlphaFold2 disordered proteins IDPs/IDRs machine-learning biophysics structural bioinformatics
Online Access:	https://www.mdpi.com/1422-0067/23/9/4591

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