Cannabidiol (CBD) and Insomnia : Literature review
Introduction Cannabidiol (CBD) is one of 113 cannabinoids identified in cannabis plants. Considered as a psycho-inactive component, recently, the Court of Justice of the European Union published a ruling in which it establishes that cannabidiol extracted from the cannabis plant should not be consid...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822020922/type/journal_article |
| _version_ | 1797616536318377984 |
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| author | T. Gutierrez Higueras F. Calera Cortés E.D. Servin López L. Montes Arjona S. Sainz De La Cuesta Alonso S. Vicent Forés |
| author_facet | T. Gutierrez Higueras F. Calera Cortés E.D. Servin López L. Montes Arjona S. Sainz De La Cuesta Alonso S. Vicent Forés |
| author_sort | T. Gutierrez Higueras |
| collection | DOAJ |
| description |
Introduction
Cannabidiol (CBD) is one of 113 cannabinoids identified in cannabis plants. Considered as a psycho-inactive component, recently, the Court of Justice of the European Union published a ruling in which it establishes that cannabidiol extracted from the cannabis plant should not be considered a drug under the United Nations Single Convention on Narcotic Drugs of 1961. Due to increased publicity on social media of the supposed benefits of this product, in addition to the lack of clear regulations, it is becoming a widely used treatment for sleep disorders.
Objectives
To analyse literature for the effect of CBD in sleep disturbances, emphasizing advantages and disadvantages of its use.
Methods
We carried out a literature review in Pubmed choosing those articles focused on effect of CBD in sleep disturbances.
Results
The review of the effect of CBD on sleep cycle suggest that medium to high doses increased REM sleep latency, and medium-low doses decreased REM sleep latency. No evidence of withdrawal syndrome was found with abrupt discontinuation of short-term treatment with CBD.
Conclusions
Most of the literature revised shows that the data was taken by self-questionares to CBD users. Studies suggest that a short use of medium to hight doses of CBD may improve insomnia, however, combined use with THC may result in a decrease in slow wave sleep. Longitudinal research should be done in order to understand the clinical impact of CBD on sleep.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:42:36Z |
| format | Article |
| id | doaj.art-dfec6ec68ab749de9343b83b1fae6a78 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:42:36Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-dfec6ec68ab749de9343b83b1fae6a782023-11-17T05:08:18ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S809S80910.1192/j.eurpsy.2022.2092Cannabidiol (CBD) and Insomnia : Literature reviewT. Gutierrez Higueras0F. Calera Cortés1E.D. Servin López2L. Montes Arjona3S. Sainz De La Cuesta Alonso4S. Vicent Forés5Reina Sofia University Hospital, Psychiatry, Córdoba, SpainHospital Reina Sofía Córdoba, Psychiatry, Cordoba, SpainReina Sofia University Hospital, Psychiatry, Córdoba, SpainReina Sofia University Hospital, Psychiatry, Córdoba, SpainHospital Reina Sofía Córdoba, Psychiatry, Cordoba, SpainHospital Reina Sofía Córdoba, Psychiatry, Córdoba, Spain Introduction Cannabidiol (CBD) is one of 113 cannabinoids identified in cannabis plants. Considered as a psycho-inactive component, recently, the Court of Justice of the European Union published a ruling in which it establishes that cannabidiol extracted from the cannabis plant should not be considered a drug under the United Nations Single Convention on Narcotic Drugs of 1961. Due to increased publicity on social media of the supposed benefits of this product, in addition to the lack of clear regulations, it is becoming a widely used treatment for sleep disorders. Objectives To analyse literature for the effect of CBD in sleep disturbances, emphasizing advantages and disadvantages of its use. Methods We carried out a literature review in Pubmed choosing those articles focused on effect of CBD in sleep disturbances. Results The review of the effect of CBD on sleep cycle suggest that medium to high doses increased REM sleep latency, and medium-low doses decreased REM sleep latency. No evidence of withdrawal syndrome was found with abrupt discontinuation of short-term treatment with CBD. Conclusions Most of the literature revised shows that the data was taken by self-questionares to CBD users. Studies suggest that a short use of medium to hight doses of CBD may improve insomnia, however, combined use with THC may result in a decrease in slow wave sleep. Longitudinal research should be done in order to understand the clinical impact of CBD on sleep. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822020922/type/journal_articleTreatmentCBDInsomniasleep |
| spellingShingle | T. Gutierrez Higueras F. Calera Cortés E.D. Servin López L. Montes Arjona S. Sainz De La Cuesta Alonso S. Vicent Forés Cannabidiol (CBD) and Insomnia : Literature review European Psychiatry Treatment CBD Insomnia sleep |
| title | Cannabidiol (CBD) and Insomnia : Literature review |
| title_full | Cannabidiol (CBD) and Insomnia : Literature review |
| title_fullStr | Cannabidiol (CBD) and Insomnia : Literature review |
| title_full_unstemmed | Cannabidiol (CBD) and Insomnia : Literature review |
| title_short | Cannabidiol (CBD) and Insomnia : Literature review |
| title_sort | cannabidiol cbd and insomnia literature review |
| topic | Treatment CBD Insomnia sleep |
| url | https://www.cambridge.org/core/product/identifier/S0924933822020922/type/journal_article |
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