SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI
The research about the influence of NaOH concentrations and reaction temperature to O-Carboxymethyl Chitosan (O-CMC) synthesis and it is antibacterial application was done. This research intent on detect NaOH concentration and reaction temperature that resulting of O-CMC with highest of yield, solub...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Tadulako University
2017-04-01
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| Series: | Kovalen: Jurnal Riset Kimia |
| Online Access: | https://bestjournal.untad.ac.id/index.php/kovalen/article/view/8231 |
| _version_ | 1827913173390327808 |
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| author | Jaya Hardi Nurakhirawati Nurakhirawati Ahmad Ridhay Musdalifah Musdalifah |
| author_facet | Jaya Hardi Nurakhirawati Nurakhirawati Ahmad Ridhay Musdalifah Musdalifah |
| author_sort | Jaya Hardi |
| collection | DOAJ |
| description | The research about the influence of NaOH concentrations and reaction temperature to O-Carboxymethyl Chitosan (O-CMC) synthesis and it is antibacterial application was done. This research intent on detect NaOH concentration and reaction temperature that resulting of O-CMC with highest of yield, solubility, and substitution degrees, and also to find out FTIR spectrum and antibacterial activity of O-CMC. The produce of O-CMC was done by using a Completely Randomized Design (CRD) with the variation of NaOH concentration of 20%, 30%, 40%, 50%, and 60%, and also reaction temperature of 20, 30, and 40oC. The result was showed that on the NaOH concentration of 60% (w/v) and temperature of 30oC was resulted highest of yield, solubility, and substitution degrees of 41.5%, 31 g/L, and 0.67, respectively. FTIR spectrum was showed that bending vibration of primary amine (-NH2) give two bands for O-CMC. The broadest inhibition area of O-CMC (1.43 cm) was showed on Salmonella sp.
Keywords: chitosan, O-CMC, substitution degree, antibacterial |
| first_indexed | 2024-03-13T02:26:33Z |
| format | Article |
| id | doaj.art-dfecf35a4922460684341b85bc2e1960 |
| institution | Directory Open Access Journal |
| issn | 2477-5398 |
| language | English |
| last_indexed | 2024-03-13T02:26:33Z |
| publishDate | 2017-04-01 |
| publisher | Tadulako University |
| record_format | Article |
| series | Kovalen: Jurnal Riset Kimia |
| spelling | doaj.art-dfecf35a4922460684341b85bc2e19602023-06-30T02:10:18ZengTadulako UniversityKovalen: Jurnal Riset Kimia2477-53982017-04-013133408231SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERIJaya Hardi0Nurakhirawati Nurakhirawati1Ahmad Ridhay2Musdalifah MusdalifahOrganic Chemistry, Chemistry Department, Tadulako UniversityPhysical Chemistry, Chemistry Department, Tadulako UniversityOrganic Chemistry, Chemistry Department, Tadulako UniversityThe research about the influence of NaOH concentrations and reaction temperature to O-Carboxymethyl Chitosan (O-CMC) synthesis and it is antibacterial application was done. This research intent on detect NaOH concentration and reaction temperature that resulting of O-CMC with highest of yield, solubility, and substitution degrees, and also to find out FTIR spectrum and antibacterial activity of O-CMC. The produce of O-CMC was done by using a Completely Randomized Design (CRD) with the variation of NaOH concentration of 20%, 30%, 40%, 50%, and 60%, and also reaction temperature of 20, 30, and 40oC. The result was showed that on the NaOH concentration of 60% (w/v) and temperature of 30oC was resulted highest of yield, solubility, and substitution degrees of 41.5%, 31 g/L, and 0.67, respectively. FTIR spectrum was showed that bending vibration of primary amine (-NH2) give two bands for O-CMC. The broadest inhibition area of O-CMC (1.43 cm) was showed on Salmonella sp. Keywords: chitosan, O-CMC, substitution degree, antibacterialhttps://bestjournal.untad.ac.id/index.php/kovalen/article/view/8231 |
| spellingShingle | Jaya Hardi Nurakhirawati Nurakhirawati Ahmad Ridhay Musdalifah Musdalifah SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI Kovalen: Jurnal Riset Kimia |
| title | SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI |
| title_full | SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI |
| title_fullStr | SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI |
| title_full_unstemmed | SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI |
| title_short | SINTESIS O-KARBOKSIMETIL KITOSAN PADA BERBAGAI KONSENTRASI NaOH DAN SUHU REAKSI SERTA APLIKASINYA SEBAGAI ANTIBAKTERI |
| title_sort | sintesis o karboksimetil kitosan pada berbagai konsentrasi naoh dan suhu reaksi serta aplikasinya sebagai antibakteri |
| url | https://bestjournal.untad.ac.id/index.php/kovalen/article/view/8231 |
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