Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway

Arctigenin Induces an Activation Response in Porcine Alveolar Macrophage Through TLR6-NOX2-MAPKs Signaling Pathway

Arctigenin (ARG), one of the most active ingredients abstracted from seeds of Arctium lappa L., has been proved to exert promising biological activities such as immunomodulatory, anti-viral, and anti-cancer etc. However, the mechanism behind its immunomodulatory function still remains elusive to be...

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Bibliographic Details
Main Authors: Zheng Lu, Lingling Chang, Qian Du, Yong Huang, Xiujuan Zhang, Xingchen Wu, Jie Zhang, Ruizhen Li, Zelin Zhang, Wenlong Zhang, Xiaomin Zhao, Dewen Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
arctigenin
porcine alveolar macrophage
NOX2
ROS
TLR6
MAPKs
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00475/full

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