A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report
Abstract Background Leiomyoma of the seminal vesicle is a rare leiomyoma characterized by the formation of benign leiomyomatous tissue within the seminal vesicle. Although histologically benign, excessive size can lead to urinary system disease if left untreated. Herein, we report a case of a semina...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-01-01
|
| Series: | BMC Urology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12894-022-00963-3 |
| _version_ | 1819281562254966784 |
|---|---|
| author | Xiaoyang Xu Shuang He Yangyang Li Feifei Wen Lizhen Lu Zhongze Cui Shuhua Wu |
| author_facet | Xiaoyang Xu Shuang He Yangyang Li Feifei Wen Lizhen Lu Zhongze Cui Shuhua Wu |
| author_sort | Xiaoyang Xu |
| collection | DOAJ |
| description | Abstract Background Leiomyoma of the seminal vesicle is a rare leiomyoma characterized by the formation of benign leiomyomatous tissue within the seminal vesicle. Although histologically benign, excessive size can lead to urinary system disease if left untreated. Herein, we report a case of a seminal vesicle epithelioid leiomyoma. Case presentation A 36-year-old Chinese man sought medical attention at our hospital for urination pain and hemospermia. CT showed a 5.3 cm × 5.0 cm seminal vesicle mass with a mixed density in the right seminal vesicle. The gross specimen showed light yellow, gray, and white tissues, with softness and hemorrhage in some places. Histologically, it showed classic spindle cell proliferation, with spindle cells arranged in fascicles, and mitosis was rare. Immunohistochemistry showed frequent expression of smooth muscle markers, such as calponin, SMA, and desmin. A diagnosis of epithelioid leiomyoma was proposed according to the immunohistochemical findings and morphology. The patient did not receive adjuvant therapy. There was no evidence of tumor recurrence in the 10 months after surgery. Conclusions We report the first case of epithelioid leiomyoma in the seminal vesicle. This disease should be included in the differential diagnostic list of seminal vesicle tumors with epithelioid morphology. |
| first_indexed | 2024-12-24T01:01:40Z |
| format | Article |
| id | doaj.art-dfeeea0a1ad146988b8a08402fa629e4 |
| institution | Directory Open Access Journal |
| issn | 1471-2490 |
| language | English |
| last_indexed | 2024-12-24T01:01:40Z |
| publishDate | 2022-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Urology |
| spelling | doaj.art-dfeeea0a1ad146988b8a08402fa629e42022-12-21T17:23:21ZengBMCBMC Urology1471-24902022-01-012211910.1186/s12894-022-00963-3A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case reportXiaoyang Xu0Shuang He1Yangyang Li2Feifei Wen3Lizhen Lu4Zhongze Cui5Shuhua Wu6Department of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalDepartment of Pathology, Binzhou Medical University HospitalAbstract Background Leiomyoma of the seminal vesicle is a rare leiomyoma characterized by the formation of benign leiomyomatous tissue within the seminal vesicle. Although histologically benign, excessive size can lead to urinary system disease if left untreated. Herein, we report a case of a seminal vesicle epithelioid leiomyoma. Case presentation A 36-year-old Chinese man sought medical attention at our hospital for urination pain and hemospermia. CT showed a 5.3 cm × 5.0 cm seminal vesicle mass with a mixed density in the right seminal vesicle. The gross specimen showed light yellow, gray, and white tissues, with softness and hemorrhage in some places. Histologically, it showed classic spindle cell proliferation, with spindle cells arranged in fascicles, and mitosis was rare. Immunohistochemistry showed frequent expression of smooth muscle markers, such as calponin, SMA, and desmin. A diagnosis of epithelioid leiomyoma was proposed according to the immunohistochemical findings and morphology. The patient did not receive adjuvant therapy. There was no evidence of tumor recurrence in the 10 months after surgery. Conclusions We report the first case of epithelioid leiomyoma in the seminal vesicle. This disease should be included in the differential diagnostic list of seminal vesicle tumors with epithelioid morphology.https://doi.org/10.1186/s12894-022-00963-3Seminal vesicleEpithelioid leiomyomaCase reportPathologyComputed tomography |
| spellingShingle | Xiaoyang Xu Shuang He Yangyang Li Feifei Wen Lizhen Lu Zhongze Cui Shuhua Wu A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report BMC Urology Seminal vesicle Epithelioid leiomyoma Case report Pathology Computed tomography |
| title | A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report |
| title_full | A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report |
| title_fullStr | A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report |
| title_full_unstemmed | A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report |
| title_short | A common tumor in an uncommon site: epithelioid Leiomyoma arising from the seminal vesicle—a case report |
| title_sort | common tumor in an uncommon site epithelioid leiomyoma arising from the seminal vesicle a case report |
| topic | Seminal vesicle Epithelioid leiomyoma Case report Pathology Computed tomography |
| url | https://doi.org/10.1186/s12894-022-00963-3 |
| work_keys_str_mv | AT xiaoyangxu acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT shuanghe acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT yangyangli acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT feifeiwen acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT lizhenlu acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT zhongzecui acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT shuhuawu acommontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT xiaoyangxu commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT shuanghe commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT yangyangli commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT feifeiwen commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT lizhenlu commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT zhongzecui commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport AT shuhuawu commontumorinanuncommonsiteepithelioidleiomyomaarisingfromtheseminalvesicleacasereport |