Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections
Aim: Acinetobacter baumannii is an important nosocomial pathogen. The purpose of this study was to identify risk factors and mortality of nosocomial infections caused by pan drug resistant (PDR) Acinetobacter baumannii and to characterize their effects on mortality.Patients and Methods: This study w...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Alanya Alaaddin Keykubat University
2019-10-01
|
| Series: | Acta Medica Alanya |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/en/pub/medalanya/issue/49795/543371?publisher=alku |
| _version_ | 1797913516204621824 |
|---|---|
| author | Havva Tünay Tuna Demi̇rdal Neşe Demi̇rtürk |
| author_facet | Havva Tünay Tuna Demi̇rdal Neşe Demi̇rtürk |
| author_sort | Havva Tünay |
| collection | DOAJ |
| description | Aim: Acinetobacter baumannii is an important nosocomial pathogen. The purpose of this study was to identify risk factors and mortality of nosocomial infections caused by pan drug resistant (PDR) Acinetobacter baumannii and to characterize their effects on mortality.Patients and Methods: This study was performed at the Afyonkarahisar Helath Science University, Faculty of Medicine. Nosocomial infections were defined accor-ding to the American Center for Disease Control (CDC). Patients with nosocomial infections caused by Acinetobacter baumannii were included in the study. Patients identified as PDR Acinetobacter baumannii and non-PDR Acinetobacter baumannii infection were com-pared in terms of risk factors.Results: Two different groups were constructed, one group consisting of 145 PDR and the other of 145 non-PDR Acinetobacter baumannii cases. Stay history in an internal intensive care unit (p=0.001), their duration of hospital stay (p=0.031), renal disease (p=0.003), mechanical ventilation (p=0.001), prior usage history of carbap-enem (p=0.001), presence of nosocomial pneumonia (p=0.001), were independent risk factors associated with PDR Acinetobacter baumannii infections. The mortality rate for the PDR group was 61.8% and it was 38.2% in the non-PDR group (p=0.008).Conclusion: PDR Acinetobacter baumannii infections are important nosocomial in-fections with a high mortality rate. Patients’ carbapenem usage, stay history in an internal intensive care unit, renal comorbid diseases, and a diagnosis of nosocomial pneumonia are important risk factors for PDR Acinetobacter baumannii infections. In nosocomial infections caused by PDR Acinetobacter baumannii, many risk factors were modifiable. |
| first_indexed | 2024-04-10T12:12:57Z |
| format | Article |
| id | doaj.art-dfef07ad1b76411b896775e415df129d |
| institution | Directory Open Access Journal |
| issn | 2587-0319 |
| language | English |
| last_indexed | 2024-04-10T12:12:57Z |
| publishDate | 2019-10-01 |
| publisher | Alanya Alaaddin Keykubat University |
| record_format | Article |
| series | Acta Medica Alanya |
| spelling | doaj.art-dfef07ad1b76411b896775e415df129d2023-02-15T16:15:55ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192019-10-013325426010.30565/medalanya.543371727Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii InfectionsHavva TünayTuna Demi̇rdal0Neşe Demi̇rtürkİZMİR KATİP ÇELEBİ ÜNİVERSİTESİ, TIP FAKÜLTESİAim: Acinetobacter baumannii is an important nosocomial pathogen. The purpose of this study was to identify risk factors and mortality of nosocomial infections caused by pan drug resistant (PDR) Acinetobacter baumannii and to characterize their effects on mortality.Patients and Methods: This study was performed at the Afyonkarahisar Helath Science University, Faculty of Medicine. Nosocomial infections were defined accor-ding to the American Center for Disease Control (CDC). Patients with nosocomial infections caused by Acinetobacter baumannii were included in the study. Patients identified as PDR Acinetobacter baumannii and non-PDR Acinetobacter baumannii infection were com-pared in terms of risk factors.Results: Two different groups were constructed, one group consisting of 145 PDR and the other of 145 non-PDR Acinetobacter baumannii cases. Stay history in an internal intensive care unit (p=0.001), their duration of hospital stay (p=0.031), renal disease (p=0.003), mechanical ventilation (p=0.001), prior usage history of carbap-enem (p=0.001), presence of nosocomial pneumonia (p=0.001), were independent risk factors associated with PDR Acinetobacter baumannii infections. The mortality rate for the PDR group was 61.8% and it was 38.2% in the non-PDR group (p=0.008).Conclusion: PDR Acinetobacter baumannii infections are important nosocomial in-fections with a high mortality rate. Patients’ carbapenem usage, stay history in an internal intensive care unit, renal comorbid diseases, and a diagnosis of nosocomial pneumonia are important risk factors for PDR Acinetobacter baumannii infections. In nosocomial infections caused by PDR Acinetobacter baumannii, many risk factors were modifiable.https://dergipark.org.tr/en/pub/medalanya/issue/49795/543371?publisher=alkuacinetobacter baumanniiantibiyotik direnciantimikrobiyal tedaviacinetobacter baumanniiantibiotic resistanceantimicrobial therapy |
| spellingShingle | Havva Tünay Tuna Demi̇rdal Neşe Demi̇rtürk Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections Acta Medica Alanya acinetobacter baumannii antibiyotik direnci antimikrobiyal tedavi acinetobacter baumannii antibiotic resistance antimicrobial therapy |
| title | Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections |
| title_full | Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections |
| title_fullStr | Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections |
| title_full_unstemmed | Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections |
| title_short | Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections |
| title_sort | risk factors for nosocomial pan drug resistant acinetobacter baumannii infections |
| topic | acinetobacter baumannii antibiyotik direnci antimikrobiyal tedavi acinetobacter baumannii antibiotic resistance antimicrobial therapy |
| url | https://dergipark.org.tr/en/pub/medalanya/issue/49795/543371?publisher=alku |
| work_keys_str_mv | AT havvatunay riskfactorsfornosocomialpandrugresistantacinetobacterbaumanniiinfections AT tunademirdal riskfactorsfornosocomialpandrugresistantacinetobacterbaumanniiinfections AT nesedemirturk riskfactorsfornosocomialpandrugresistantacinetobacterbaumanniiinfections |