Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study

Discovering Deleterious Single Nucleotide Polymorphisms of Human AKT1 Oncogene: An In Silico Study

Background: AKT1 is a serine/threonine kinase necessary for the mediation of apoptosis, angiogenesis, metabolism, and cell proliferation in both normal and cancerous cells. The mutations in the AKT1 gene have been associated with different types of cancer. Further, the AKT1 gene mutations are also r...

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Bibliographic Details
Main Authors: Ruojun Zhang, Nahid Akhtar, Atif Khurshid Wani, Khalid Raza, Vikas Kaushik
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Life
Subjects:
SNPs
oncogene
AKT1
kinase
Online Access:https://www.mdpi.com/2075-1729/13/7/1532

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