Biological Safety and Biodistribution of Chitosan Nanoparticles

Biological Safety and Biodistribution of Chitosan Nanoparticles

The effect of unmodified chitosan nanoparticles with a size of ~100 nm and a weakly positive charge on blood coagulation, metabolic activity of cultured cardiomyocytes, general toxicity, biodistribution, and reactive changes in rat organs in response to their single intravenous administration at dos...

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Bibliographic Details
Main Authors: Dmitry Sonin, Evgeniia Pochkaeva, Sergei Zhuravskii, Viktor Postnov, Dmitry Korolev, Lyubov Vasina, Daria Kostina, Daria Mukhametdinova, Irina Zelinskaya, Yury Skorik, Elena Naumysheva, Anna Malashicheva, Pavel Somov, Maria Istomina, Natalia Rubanova, Ilia Aleksandrov, Marina Vasyutina, Michael Galagudza
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nanomaterials
Subjects:
chitosan
polymer nanoparticles
biodistribution
blood compatibility
safety evaluation
in vivo treatment
Online Access:https://www.mdpi.com/2079-4991/10/4/810

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https://www.mdpi.com/2079-4991/10/4/810

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